Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Sost"”.
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Mechanical Properties of Bone Due to SOST Expression: A 3-Point Bending Assessment of Murine Femurs
<p>Sclerostin, a protein coded for by the SOST gene, is an osteocyte-expressed negative regulator of bone formation. The absence of SOST in the genome may have an effect on bone formation both during skeletal maturation and full maturity. This study attempts to determine significant differences in …
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Effects of scriptaid on osteocytes skeletal homeostasis and metabolic functions
… the TCA cycle. In osteocytes, PTH suppresses Sost expression (the gene encoding a potent inhibitor of bone formation) by inducing HDAC4/5 nuclear translocation and MEF2C inhibition. Recently, Scriptaid, an HDAC complex inhibitor, has been shown to induce Mef2 expression and exercise-like …
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Physical training, inflammation and bone integrity in elite female rowers
… and factors that regulate bone (sclerostin (SOST), osteoprotegerin (OPG)), and receptor activator of nuclear factor kappa-B ligand (RANKL)) and energy metabolism (insulin-like growth factor-1 (IGF-1) and leptin), and inflammation (tumor necrosis factor-α (TNF-α)) in elite heavyweight female …
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A Behavioral Study on the Adult Marmoset Interference Control in Spatial Working Memory
… a touch-screen self-ordered sequencing task (SOST), which resembles an n-back paradigm and targets updating processes in internal interference control. However, the training time for the marmoset to reach proficiency on this paradigm is long given the short marmoset lifespan. In an attempt to …
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Supporting bone regeneration: Evaluation of endocrine peptides and delivery systems for local application of lactoferrin
… to rhPTH(1-34) and decreased expression of Sost. Both irisin and orexin enhanced bone marrow stromal cell differentiation into adipocytes, and orexin also increased osteoblast proliferation. Irisin and orexin did not affect matrix mineralisation by osteoblasts, osteocyte function or …
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Kalirin : novel role in osteocyte function
… the mRNA levels of osteoprotegerin (OPG) and SOST, which are important for controlling osteoclast differentiation and Wnt signaling leading to bone formation, respectively, were reduced in Kal-KO osteocytes. Next, the role of Kalirin in osteocyte morphology and function was further examined. …
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The effect of bone anabolic stimuli on human osteoblast to osteocyte transition.
… (EDS). Levels of mRNAs encoding the OY markers, SOST, E11 and dentin matrix protein 1 (DMP1), were elevated in the mineralised cultures indicating promotion of osteoblast to OY transition. Gene expression was differentially regulated by Ca²⁺. The expression of the osteoclast inhibitor, OPG, was …