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Showing 1 to 1 of 1 for “"Sonic Hedgehog Medulloblastoma"”.
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The Generation of Alternative Transcripts as a Means of Regulating Phosphorylation in Sonic Hedgehog Medulloblastoma
… mechanism for regulation at the mRNA level. The sonic hedgehog (SHH) subtype of medulloblastoma (MB), the most common malignant pediatric cerebellar tumor, arises from granule neuron precursors (GNPs) through aberrant SHH signaling. Murine postnatal day 7 (P7) GNPs are highly proliferative and …