Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 67 for “"Somatosensory cortex"”.
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Role of mGluR5 and FMRP in mouse primary somatosensory cortex
… exaggerated in FXS (Bear et al., 2004). Primary somatosensory cortex (S1) of rodents provides an excellent model system to study the role of MR genes in development because of its stereotypic, glutamate receptor-dependent, anatomical development (Barnett et al., 2006b; Erzurumlu and Kind, 2001). …
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Magnetic source imaging of tactile evoked activity in the human secondary somatosensory cortex
In der vorliegenden Arbeit wurde die Antwort des menschlichen Gehirns auf taktile Fingerstimulation mittels Magnetoenzephalographie (MEG) untersucht. Zur Darstellung des zeitlichen Aktivitätsverlaufs im primären (SI) und sekundären (SII) somatosensorischen Kortex wurde räumlich-zeitliche …
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Somatotopic mapping of the human somatosensory cortex using functional magnetic resonance imaging (fMRI)
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1996.
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fMRI for mapping the plastic somatotopy of primary somatosensory cortex - Development and clinical applications
… thesis, methods for fMRI mapping of the primary somatosensory cortex (S1) are optimised and subsequently applied in studies where a plastic reorganisation of S1 is hypothesised. Initially, the impact of spatial resolution and smoothing on fMRI data of detailed S1 activation was investigated using …
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Postnatal development of the somatosensory cortex in a rat model of Fragile X Syndrome
… first 4 weeks of postnatal development of the somatosensory cortex (S1) in a rat model of FXS, by characterizing the electrophysiological properties and morphology of S1 neurons, combined with an investigation of interneuron density. Using whole-cell patch clamp recordings from layer 4 of S1, I …
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A Rodent Animal Model for Forelimb to Lower Jaw Reorganization in Primary Somatosensory Cortex (SI) Barrel Field
… cortical reorganization in rat primary somatosensory (SI) cortex that follows forelimb deafferentation. The majority of human patients suffering from limb loss or brachial plexus avulsion injury, as well as patients that receive brachial plexus anesthesia, report phantom limb …
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THE EFFCT OF LOW-LEVEL LEAD ON SEROTONIN EXPRESSION IN THE DEVELOPING MOUSE SUPERIOR OLIVARY COMPLEX AND SOMATOSENSORY CORTEX
… LSO neurons and thalamocortical neurons of the somatosensory system, transiently take up 5-HT from the extracellular environment through the transient expression of the serotonin reuptake transporter SERT. Maintenance of appropriate 5-HT levels is important for development of these sensory …
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THE EFFCT OF LOW-LEVEL LEAD ON SEROTONIN EXPRESSION IN THE DEVELOPING MOUSE SUPERIOR OLIVARY COMPLEX AND SOMATOSENSORY CORTEX
… LSO neurons and thalamocortical neurons of the somatosensory system, transiently take up 5-HT from the extracellular environment through the transient expression of the serotonin reuptake transporter SERT. Maintenance of appropriate 5-HT levels is important for development of these sensory …
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THALAMIC PROJECTIONS TO MOTOR PREFRONTAL, AND SOMATOSENSORY CORTEX IN THE SHEEPSTUDIED BY MEANS OF THE HORSERADISH PEROXIDASE RETROGRADE TRANSPORT METHOD
IN THIS STUDY THE MOTOR, PREFRONTAL AND SOMATOSENSORY AREAS OF THE SHEEP CEREBRAL CORTEX WERE DEFINED ON THE BASIS OF THEIR THALAMIC AFFERENTS TRACED WITH THE HORSERADISH PEROXIDASE METHOD. THE MOTOR AREA (AREAS 4 AND 6) OCCUPIES THE CRUCIATE GYRUS. IT RECEIVES A SUBSTANTIAL PROJECTION FROM THE …
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The effect of a vibration intervention on the somatosensory Cortex of the brain in patients with sensory peripheral Neuropathy secondary to type ii diabetes mellitus
… potential changes in activity within the somatosensory cortex of the brain. Study aim: This study aims to determine the effect of a vibration intervention, applied to the plantar surface of the foot of patients with SPN secondary to DM II on the somatosensory cortex of the brain. The …
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Investigation of the Clinical Utility of the Spatio-Spectral Dynamics of Sensorimotor ECoG in Response to Different Somatosensory Stimulation Modalities in Human Subjects
… visual assessment of the phase reversal of the somatosensory evoked potentials (SSEPs) is employed to delineate the central sulcus (CS). However, proper assessment of the phase reversal in the SSEP waveform is challenging due to the variations in the waveform morphology across subjects and the …
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The generation and characterization of transgenic mice expressing modifiers of Rho GTPases
… the postnatal mouse brain, and we found that the somatosensory cortex in the adult mouse brain contained more severe involutions and aggregations of the cells in specific area of somatosensory cortex in brain, particularly in layer IV. Also, the barrel-like discontinuous pattern was more extended …
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Exploring lateralized sensorimotor processing using somatosensory evoked potentials
… data to support their findings. By utilizing somatosensory evoked potentials (SEPs) we can gain insight into the underlying neurological processes at the levels of the spinal cord and the cortex in response to movement and motor learning. The research conducted showed greater accuracy in the …
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Characterization of CPG15 during cortical development and activity dependent plasticity
… and synaptic maturation, is regulated in the somatosensory cortex by sensory experience capable of inducing cortical plasticity. Using in situ hybridization, we monitored cgp15 expression in 4-week-old mouse barrel cortex after trimming all whiskers except D1. We found that cpgl5 expression is …
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Sensitive skins and somatic processing for affective and sociable robots based upon a somatic alphabet approach
… (FSRs) and embedded processing was created. Somatosensory inspired algorithms for calculating the location, direction of motion, and orientation with a set of these sensors forms the first stage in the design of a "Virtual Somatosensory Cortex." A multi-modal (temperature, electric field …
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Examination of neocortical plasticity during forebrain-dependent trace-associative learning tasks
… because it requires an intact neocortex and hippocampus (Solomon et al., 1986; Moyer et al., 1990; Kim et al., 1995; Weiss et al., 1999a; Takehara et al., 2002; Galvez et al., 2007). Using the trace-eyeblink conditioning paradigm with whisker stimulation as the CS …
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A tailored biocompatible neural interface for long term monitoring in neural networks
… activity were obtained in both cerebellum and cortex cerebri (papers I-III). In paper IV, we evaluated the importance of mechanical flexibility and demonstrated that probe flexibility has a significant impact on the astroglial scar, but not on the loss of neurons nearby. Moreover, by embedding …
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Using single nucleus RNA-seq to determine the effect of immunosuppression on the transcriptional activity of resident CNS cells in a mouse model of CNS-TB
… Mycobacterium Tuberculosis was injected into the somatosensory cortex of the treatment groups, with control samples receiving a saline injection. Brains were harvested at 9- and 17-days post inoculation. Following library generation, removal of ambient RNA and data processing using Seurat, …
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Effects of Whisker-Trimming on GABAA Receptors in S1 Cortex
… GABA receptors, in deprived areas of visual and somatosensory cortex. Those studies focused on layer 4, a recipient of direct thalamocortical sensory input. However, supragranular layers 2/3 have been recently identified as a major locus of functional plasticity in sensory deprivation and …
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Causal evidence for the behavioral impact of oscillations in neocortex and hippocampus
… types of oscillations,'gamma rhythms in the neocortex (30-80 Hz) and theta rhythms in the hippocampus (4-12 Hz). In both cases, I use light-gated ion channels to manipulate spike activity on a cycle-by-cycle basis in awake, behaving mice. By rhythmically stimulating fast-spiking interneurons in …
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