Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 94 for “"Solvent Evaporation"”.
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Controlled emulsion droplet solvent evaporation for particle production
… typically used. We employ the emulsion droplet solvent evaporation method, which is extremely versatile, to create, for example, magnetic nanoparticles, polymeric Janus beads, and crystalline particles. The emulsion droplets act as confined spaces, or templates, within which the particles can …
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Predicting aqueous solubility of pharmaceutical agents by solid dispersion prepared by solvent evaporation method
… descriptors of the active agent, polymer, and solvent with solubility enhancement. The partition co-efficient, hydrogen bonding and solubility parameters of polymer and water were found to influence the aqueous solubility of the poorly-soluble compounds. Aqueous solubility of a compound had an …
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Microencapsulation studies with P(HB-HV) polymers
… processes, based upon the concept of solvent evaporation, have been employed within these studies to prepare microparticles from poly--hydroxybutyrate homopolymers and copolymers thereof with 3-hydroxyvalerate [P(HB-HV) polymers]. Variations in the preparative technique have …
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The effects of evaporation rate, solvent, and substrate on the surface segregation of block copolymers
… of [PDMS/PSF] blends cast at several rates of solvent evaporation, and cast on several substrates were measured. Surface concentration profiles of poly(styrene-butadiene-styrene) poly(styrene-isoprene-styrene) [SIS] triblock [SBS] and copolymers cast at several rates of solvent evaporation, and …
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Preparation and Characterization of Bio-based PCM Microcapsules for Thermal Energy Storage
… of 100% bio-based (organic) PCM microcapsules by solvent evaporation and oil-in-water emulsification was investigated under different conditions, resulting in optimal properties. For the second phase, the focus was on the studies of inorganic PCM, which have higher latent heat of melting, higher …
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Fabrication of carbon nanoscrolls from patterned CVD-grown graphene
… graphene into carbon nanoscrolls by solvent evaporation is attempted. Graphene is observed to roll up by 350 nm on average from unrestrained edges, forming partial nanoscrolls. Resistance is measured while regulating charge carrier concentration with Si0 2 back gate. A large …
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Microfluidic platforms for solid form screening of pharmaceutical parent compounds
… of crystallization, viz. diffusive mixing, antisolvent addition, and solvent evaporation. These platforms are compatible with a wide range of solvents typically used for pharmaceutical crystallization, suffer from minimal solvent loss (enabling long-term experiments), allow improved control over …
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Synthesis and Characterization of Multi-Functional Nanoparticles for Therapeutic and Biosensing Applications
… nanoparticles prepared using double emulsion solvent evaporation was quantified and release phases were identified. Insulin-like growth factor (IGF1)-loaded nanoparticles showed that the released protein was able to stimulate an important pathway for effective cell proliferation and cell …
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Development of Polymeric Microparticle-Based Drug Delivery System for Sustained Delivery of H2S for Treatment of Glaucoma
… Initial preparation attempts using coacervation solvent-evaporation resulted in overheating, uncontrolled solvent evaporation, polymer aggregation, and poor reproducibility. To overcome these limitations, a coacervation solvent-extraction method using a closed apparatus system was successfully …
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Modeling and experimental analysis of electrospinning bending region physics in determining fiber diameter for hydrophilic polymer solvent systems
… submicron fibers from a wide range of polymer/solvent systems that enable a variety of different applications. In electrospinning process, a straight polymer/solvent charged jet is initially formed, followed by a circular moving jet in the shape of a cone, called the bending region. The process …
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Clear, Aqueous Topical Nanomicelle Formulation For Diabetic Macula Edema
… All formulations were prepared following solvent evaporation and film rehydration method, characterized with size, polydispersity, shape, morphology, clarity/ appearance and cytotoxicity on human corneal and retinal cell lines. A specific blend of HCO and Oc-40 at a particular wt% ratio …
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Spinning of synthetic spider silk-like fibers and ex vivo rheology of spider silk
… experiments much insight was gained on how solvent removal during elongational flow (while the fiber is on the spin line) affects mechanical properties. In order to determine solvent evaporation from the fiber during spinning, the dependence of the solvent diffusion coefficient on solvent …
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Crystalline Salt Formation of an Acidic Drug Indomethacin Using Hot Melt Extrusion Technology
… drugs, it consumes large quantities of organic solvents and is a batch process. Herein, we show that the dissolution rate of indomethacin (a poorly water-soluble drug) can be increased by using hot melt extrusion of a 1:1 (mol/mol) indomethacin:tromethamine mixture to form a highly crystalline …
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Energy transfer and waveguide studies of Eu3+ and Tb3+ doped 2 SiO2-TiO2 glass prepared via the sol-gel route
… in an SiO 2 network. The third step involves solvent evaporation to eliminate residual organics and hydroxyl groups within the pores of the gel. This thesis reports on the luminescence properties of Eu 3+ and Tb 3+ within the SiO 2 -TiO 2 host prepared via the sol-gel method with both H 2 O …
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Gas Jet Process for Production of Sub-micron Fibers
… and bending instabilities and concurrent solvent evaporation. The fiber is initiated by a single liquid jet formed as the liquid emerges from each nozzle configuration. The liquid jets of diameters from around 40 µm to 600 µm are attenuated to the sub-micrometer level within a small …
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DEVELOPMENT AND CHARACTERIZATION OF POLYMER-OIL NANOSTRUCTURED CARRIER (PONC) FOR CONTROLLED DELIVERY OF ALL-TRANS RETINOIC ACID (ATRA)
… The PONC were formulated by emulsification solvent evaporation technique, which were then characterized for particle size, encapsulation efficiency, drug release and anticancer efficacy. The ATRA loaded PONC showed excellent encapsulation efficiency and release kinetics. Even after surface …
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Thermal modulation during solvent annealing of PS-PDMS block copolymer
… A variety of processing techniques including solvent vapor annealing (SVA) have been developed in order to facilitate the phase transitions of BCPs from disordered to ordered states. SVA parameters which can affect the final film morphology include the swelling thickness of the film and …
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The delivery of bioactive proteins using biodegradable microspheres
… polymers by single and double emulsion solvent evaporation and spray drying techniques. The proteins used in this study were mainly BSA, tetanus toxoid, F1 and V, Y. pestis subunit vaccines and the cytokine, interferon-gamma. The polymer chosen for use in the vaccine preparation will …
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Application of microfluidic emulsion technology to biochemistry, drug delivery and Lab-on-a-Chip programmability
… systems. Coupled with the bulk method of solvent evaporation, microspheres with a tunable range of volumes spanning four orders of magnitude are generated and characterized using this rapid and flexible prototyping technique. Finally, a programmable microfluidic system platform using …
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Specific ion effects on transient polymers: a new strategy for programmable microcapusles
… payload release. In Chapter 2, a rapid solvent evaporation strategy was developed to prepare transient polymer microcapsules with a low-ceiling-temperature polymer, cyclic poly(phthalaldehyde) (cPPA), as the shell wall materials. Chapter 3 described an ion co-activation effect that …
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