Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Soluble endoglin"”.
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Lösliches Endoglin (sCD105) : diagnostische Wertigkeit bei chronischen Lebererkrankungen und funktionelle Bedeutung für die Signaltransduction von transforming growth factor (TGF-beta)
… the diagnostic potential and value of solube endoglin in patients with liver cirrhosis at high-risk of HCC was investigated. In addition, we elucidated the functional impact of heterologously expressed soluble endoglin on TGF-b1/Smad3 signaling by using an artificial reporter system for the …
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Preeclampsia Link to Gestational Hypoxia
… factor α and the anti-angiogenic factors soluble fms-like tyrosine kinase and soluble endoglin. Upstream adverse consequences on the hypoxic ewe included evidence of an angiogenic imbalance in maternal plasma, increased constrictor reactivity in isolated uterine and femoral arteries, …
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Preeclampsia, Autoimmunity and The At1 Receptor
… and increases in the anti-angiogenic factors soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin (sEng). These experiments were also carried out in non-pregnant animals who did not share the same symptoms. This suggests that pregnancy is a requirement for the full spectrum of …
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Clinical utility of 3D power doppler ultrasound and maternal biomarkers in the prediction of pre-eclampsia in high-risk pregnancies
… (PAPP-A), Placental like Growth Factor (PlGF), soluble Fms-like tyrosine kinase (sFLt-1) and soluble Endoglin (sEng)) measured in the first and second trimesters of pregnancy to predict pre-eclampsia in high-risk women.<br/><br/>To determine the added clinical utility and predictive value of …
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Evaluation of suboptimal health status and prospective levels of oxidative stress biomarkers and angiogenic growth mediators with placental anatomy and pathology in normotensive and preeclamptic births
… vascular endothelial growth factor-A [VEGF-A], soluble endoglin [sEng] and soluble VEGF receptor-1 also known as soluble fms-like tyrosine kinase [sFlt-1]) in addition to OS biomarkers (8-epiprostaglandinF2 alpha [8-epi-PGF2α], 8-hydroxy-2-deoxyguanosine [8-OHdG] and total antioxidant capacity …
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Markers and mechanisms of pre-eclampsia in pregnancies complicated by diabetes
… release of two anti-angiogenic factors, soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin (sEng) from placental trophoblasts into the maternal circulation promotes endothelial dysfunction associated with pre-eclampsia. The aim of this thesis was to investigate whether …
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Population pharmacokinetic modelling for dose optimization of esomeprazole to treat early-onset preeclampsia
… data showing it lowers concentrations of soluble fms like tyrosine kinase 1 (sFlt-1) and soluble endoglin (sEng), pathognomonic biomarkers identified in preeclampsia. A randomized controlled trial, Preeclampsia Intervention with Esomeprazole (PIE) trial, was conducted in South African …