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  1. Regulating the bioactivity of placental growth factor in the aging outer retina as a new therapeutic approach to age-related macular degeneration

    … shown to propagate retinal pathology in animal models. Reports also suggest that PlGF can induce epithelial cell dysfunction and its inhibition has shown efficacy in a mouse model of GA. In this thesis, it was hypothesised that PlGF can induce dysfunction of retinal pigment epithelium (RPE), and …

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