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Showing 1 to 20 of 20 for “"Sodium butyrate"”.
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Investigating the potential of Sodium Butyrate to Control Salmonella Enteritidis in Poultry
… human infection. Short chain fatty acids such as butyrate are microbial metabolites known to modulate inflammatory response. In this dissertation, the effect of sodium butyrate on the colonization of SE in primary chicken enterocytes and chicken macrophages was investigated. In addition, the …
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Heat shock protein 27 inhibition of apoptosis in human breast cancer cells
… Hsp 27 protects cells from apoptosis induced by Sodium Butyrate. In this study, we treated estrogen receptor negative human breast cancer cells with apoptotic inducers such as Sodium Butyrate, Staurosporine, Vitamin E Succinate and Cycloheximide. The cells that constitutively expressed Hsp 27 had …
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Pancreatic peptide hormone expression in the RINm5F cell line
… insulin after cultures had been exposed to 2mM sodium butyrate for three days. Although positively stained cells were observed by immunoperoxidase or immunofluorescence microscopy in sodium butyrate-treated cultures, staining was barely above that of background staining in peroxidasestained …
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DNA synthesis and methylation in normal and transformed cells
… of a known inducer of gene expression, sodium butyrate, were examined on these three cell lines as well. During a 16-20 hour treatment period, at butyrate concentrations of between 5 and 20 mM, no adverse effect on cell morphology was observed. Cell growth, in the presence of butyrate …
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Environmental, Biochemical, and Dietary Factors that Influence Rumen Development in Dairy Calves
… meta-analysis and to explore the effects of sodium butyrate and lipopolysaccharide (LPS) on rumen development in calves through experiment. In the first study a meta-analysis was performed to summarize the literature on calf performance and derive equations that relate rumen (e.g., rumen pH, …
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Molecular mechanisms of strain-stimulated intestinal epithelial cell differentiation and migration
… 3 reduction also prevented DPPIV induction by sodium butyrate (1mM) or TGF-â (0.1ng/ml), two unrelated differentiating stimuli. However, Shlafen-3 reduction by siRNA did not prevent the mitogenic effect of strain or that of EGF. Blocking Src and PI-3-kinase prevented strain induction of …
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MUSCLE-SPECIFIC MECP2 MISEXPRESSION INDUCES SKELETAL AND VISCERAL MUSCLE DEFECTS RESCUED BY BUTYRATE SUPPLEMENTATION IN DROSOPHILA
… short-chain fatty acids (SCFAs) - specifically butyrate - as chromatin-targeting interventions. Results Because Drosophila lacks an endogenous MECP2 gene, we used transgenic lines overexpressing either wild-type or mutant human MECP2. Using the Gal4/UAS system, tissue-specific expression …
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Development of microelectrode arrays for real-time monitoring of alkaline phosphatase release from cells in clinical analysis
… the colon cancer cell line. A concentration of sodium butyrate of 0.5mM and 1 mM allowed impedance of 550 Ω and 400 Ω compared to the control and to 600 Ω for untreated cells. This indicated a correlation between the cell response and the concentration of sodium butyrate, which suggested that …
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CaV1.3 Ion channel expression and hormone therapy in prostate cancer
… A and the histone deacetylase inhibitor, sodium butyrate. Overall, the results of this study show that CaV1.3 is relevant to AR-positive and androgen-sensitive PCa and is associated with neuroendocrine differentiation. ENZ treatment promotes CaV1.3 plasma membrane localisation and …
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Effects of Commercial Feed Additives on Growth Performance and Gut Microbiota of Nursery Pigs
… of 0.035% (SBA0.035) or 0.070% (SBA0.070) sodium butyrate in a diet containing 0.5% benzoic acid improved the growth performance of weaning pigs. The SBA0.035 diet revealed the greatest gut microbial diversity and the enrichment of several potentially beneficial bacterial taxa such as …
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Testing the Anti-Inflammatory Effects of Dietary Phytochemicals in Intestinal Inflammation Models
… TNF-stimulated colonoids, undifferentiated and sodium butyrate differentiated HT-29 cells. CA pre-treatment upregulated LCN2 (NGAL encoding gene) mRNA expression and decreased NGAL protein expression and secretion while SFN downregulated transcription and translation. In HT-29 cells, CA and SFN …
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Baculovirus as a gene delivery and expression vector in mammalian cells
… between two- to 10-fold in the presence of sodium butyrate or hydroxyurea alone and significantly improved egfp (enhanced green fluorescence protein) expression (~40-fold) when both chemicals were used in combination. Subsequently, in the second part of this study an in vitro culture model …
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Evaluation of the Role of Epstein-Barr virus and Cellular Gene Expression in Paediatric and Adult Transplant Recipients
… following 12-O-tetradecanoyl-13-phorbol acetate/sodium butyrate (TPA/NaB) induction of Raji cells. We identified 22 highly induced EBV genes (>90-fold) at 24 hrs post-induction. Using genome-wide Affymetrix microarrays, we identified cellular genes that were highly differentially expressed and …
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Effect of Feed Additives and Toxic Elements on Swine Growth Performance, Nutrient Digestibility, Immune Function and Reproductive Performance
… 0.50% peptide (0.5P); (7) 0.25% peptide + 0.1% sodium butyrate and 0.5% benzoic acid (PSB). In phase 3, all pigs were fed a common diet. Treatments in Exp 2 during phase 1 to 3 consisted of: (1) control diet, formulated to meet NRC, (2012) nutrient requirements without CSM (0% G); (2) inclusion …
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Effects of organophosphates on neural and purified liver tissue transglutaminase
… externalisation of TGase 2. In the presence of sodium butyrate, rat C6 glial cells differentiated into an astrocyte phenotype. Differentiation of the cells was associated with an increase in the activity, protein levels and gene expression of TGase 2. Differentiation in the presence of CPF or …
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Development of in vitro infant intestinal models to assess responses to infant formulae
… treated with the short-chain fatty acid salt sodium butyrate (NaB), previously reported to increase permeability without harm. High NaB concentrations (50–125 mM) reduced transepithelial electrical resistance (TEER) and increased paracellular permeability of Caco-2 monolayers in a …
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Studies on the Complement Receptor of a Human Lymphoblastoid Cell Line
… of compounds (BrdU, DMSO, 2-deoxyglucose and sodium butyrate) had no effect. Neither did mixing CR+ and CRcells, nor growing CR- cells in medium conditioned by CR+ cells. There was an apparent increase in the number of CR- clones produced by the picked single cell cloning method (in which …
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EFFECTS OF HISTONE DEACETYLASE INHIBITORS ON ENERGY METABOLISM
… recent study reported that supplementation with sodium butyrate, a dietary component active as HDAC inhibitor, promotes energy expenditure and mitochondrial function in mice fed with a high fat diet212. Given the importance of skeletal muscle metabolism in insulin resistance/diabetes, and given …
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Transcriptomic analyses of Clostridium beijerinckii NCIMB 8052 during transition from acidogenesis to solventogenesis and under butyrate supplemented conditions
… pathway switch during the fermentation. Butyrate has long been suggested as a potential triggering factor for the solventogenesis switch during the ABE fermentation. In this study, sodium butyrate was added to the chemically defined MP2 medium for ABE fermentation with C. beijerinckii …
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Genistein suppresses colon cancer metastasis through epigenetic regulations
… (HDAC) inhibitors trichostatin A (TSA) and sodium butyrate (NaBt) both significantly increased the mRNA expression of Wnt5a in SW620. NaBt treatment increased β-catenin signaling and diminished the difference in cell adhesion ability between SW480 and SW620, suggesting that the HDAC …