Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Sodium Arsenite"”.
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Role of Sodium Arsenite in Atherogenesis
… the time- and concentration-dependent effects of sodium arsenite [As(III)] on the development of atherosclerosis in ApoE-/- /LDLr-/- mice, (2) determining whether As(III)-induced peroxynitrite activates protein kinase C (PKC) isotypes, α and β, in human aortic endothelial cells (HAECs) and (3) …
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Role of Sodium Arsenite in Atherogenesis
… the time- and concentration-dependent effects of sodium arsenite [As(III)] on the development of atherosclerosis in ApoE-/- /LDLr-/- mice, (2) determining whether As(III)-induced peroxynitrite activates protein kinase C (PKC) isotypes, α and β, in human aortic endothelial cells (HAECs) and (3) …
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Disruption of 8-hydroxy-2'-deoxyguanosine DNA Glycosylase (OGG1) Antioxidant Response Capacity by Sodium Arsenite
… in superoxide dismutase activities subsequent to arsenite exposure in actively dividing and NGF treated PC12 cells. Assessment of Ogg1 activity and mRNA levels demonstrated a significant decrease for both measures subsequent to arsenite exposure. The effect seen was due in large part to …
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Disruption of 8-hydroxy-2'-deoxyguanosine DNA Glycosylase (OGG1) Antioxidant Response Capacity by Sodium Arsenite
… in superoxide dismutase activities subsequent to arsenite exposure in actively dividing and NGF treated PC12 cells. Assessment of Ogg1 activity and mRNA levels demonstrated a significant decrease for both measures subsequent to arsenite exposure. The effect seen was due in large part to …
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Aquaria studies on the uptake of arsenic 74 labeled sodium arsenite by components of an aquatic ecosystem
Thesis (M.S.)--Michigan State University. Dept. of Fisheries and Wildlife, 1966
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Ruolo della TDP-43 nella formazione dei granuli da stress nella Sclerosi Laterale Amiotrofica
… and healthy controls. After treatment with sodium arsenite (0,5 mM), for 30 and 60 minutes, we observed a significantly higher number of cells exhibiting stress granules, identified by immunostaining for specific markers (TIA-1 and HuR), in fibroblasts from healthy controls compare with …
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STRESS GRANULES MODULATE SYK TO CAUSE MICROGLIAL DYSFUNCTION IN ALZHEIMER’S DISEASE
… brain microglia, when stressed by exposure to sodium arsenite or Aβ(1-42) peptides or fibrils, form extensive stress granules to which the tyrosine kinase, SYK, is recruited. SYK enhances the formation of stress granules as evidenced by the inhibition of stress granule formation by small …
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Characterization of arsenic-binding siderophores from environmental bacteria and evaluation of their role in arsenic tolerance
… with arsenic (iron-free M9 medium with sodium arsenite). HPLC analysis of the extracts for both culture conditions showed the presence of a single compound with both an iron-chelating and an arsenic-binding activity. Analyses by nuclear magnetic resonance (NMR) spectroscopy and mass …
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AGGREGATION MECHANISMS OF TDP-43 PROTEIN IN RESPONSE TO STRESS IN AMYOTROPHIC LATERAL SCLEROSIS AND THERAPEUTIC APPROACHES
… induced a chronic and mild oxidative insult by sodium arsenite (ARS) in human neuroblastoma SK-N-BE cells and ALS patient-derived primary fibroblasts, induced pluripotent stem cells (iPSCs)-motor neurons and brain organoids. As a readout of TDP-43 functionality, we tested its subcellular …
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Stress response genes in the human proximal tubules
… when the cells were subjected to 100 muM sodium arsenite or 53.4 muM CdCl 2 for 4 hrs. These findings were in contrast to those found previously with mortal human proximal tubule (HPT) cells, where acute stress by all three stimuli elicited marked increases in hsp 27, hsp 60 and hsp 70 …
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RNA modifications and processing in cell homeostasis and in response to oxidative stress
… stress, I exposed wildtype and patient cells to sodium arsenite and measured the abundance of tRNA-derived fragments and occurrence of methylation events. With this I discovered unique tRNA fragmentation patterns and global RNA methylation profiles for wildtype and NSun2-depleted cells, that can …
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Investigating the cytoskeleton and microtubule-based transport with in situ cryo-electron tomography
… dynein-dynactin complexes. I next trialled a sodium arsenite (AS)-induced dynein-driven organelle clustering system. While many instances of cargo in the vicinity of microtubules were observed, no putative dynein-dynactin complexes were observed, likely as a result of the thickness of the …
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Regulation of the beta7 integrin gene in T cells: role of the MAPK signalling pathways
… the synthesis of α4 transcripts. Conversely, sodium arsenite which induces JNK and p38 upregulated nascent synthesis of α4 and β7 RNA transcripts. SB203580 blocked the binding of nuclear factors to TGFBRR-1, and ATF-2 binding to nucleotide position -699 to -689. Similarly, SP600125 blocked the …