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Showing 1 to 2 of 2 for “"Snm1B"”.
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Elucidation of Snm1B Function
<p>The protein Snm1B binds to the telomere binding protein TRF2 to help protect telomeres from DNA damage during S phase. In addition, Snm1B protects DNA from agents that induce interstrand crosslinks (ICLs), lethal lesions that covalently attach the opposite strands of DNA together. To elucidate …
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PARKIN, BLM AND EXO1: INVOLVEMENT IN POST-NER ACTIVITY IN NON-REPLICATING CELLS
… exonuclease, as well as other proteins such as SNM1b. We believe that this project sheds more light on the molecular mechanisms involved in the processing of closely spaced opposing lesions, in different non-cycling cell models. Indeed, we discovered that both Parkin and BLM have a role in COLs …