Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"Small regulatory RNA"”.
-
Characterizing a Small Regulatory RNA in Brucella abortus Linked to Outer Membrane Stress Resistance
… macrophages and dendritic cells. Numerous small regulatory RNAs (sRNAs) were found to be expressed by B. abortus, and it was hypothesized that they may be important for virulence. One sRNA, when deleted, was shown to be linked to outer membrane stress resistance and was named MssR (membrane …
-
Investigating Hfq-dependent Small Regulatory RNA, Bsr34, and Its Roles in Brucella abortus Physiology and Pathogenicity
… gene regulation for survival within host cells. Small regulatory RNAs (sRNAs), often chaperoned by Hfq, are key post-transcriptional regulators of bacterial virulence and stress adaptation, yet remain largely uncharacterized in Brucella. Following the identification of Hfq-associated sRNA …
-
Outer Membrane Porin Regulation among Different Sequence Types of Escherichia coli Clinical Isolates
… coli sequence types by comparing steady-state mRNA levels, mRNA half-life, small regulatory RNA (sRNA) expression, and protein production. It was hypothesized that the regulation of porin production in clinical isolates of E. coli would involve sRNAs and be dependent upon sequence type, …
-
Viengrandines mažąsias RNR modifikuojančių gyvūnų Hen1 metiltransferazių taikymas RNR žymėjimui ir sekoskaitai /
… of the 3'-terminal nucleotide in a subset of small non-coding RNAs. This modification protects small RNAs from degradation, meanwhile the deficiency of the Hen1 protein causes detrimental phenotypic changes to particular organisms. Current work presents the first detailed characterization of …
-
Transposon Mutagenesis Facilitates Discovery Of Genotype-Phenotype Associations and Functional Interrogation of the <i>Mycobacterium Kansasii</i> Genome
… to a gene encoding a conserved mycobacterial small regulatory RNA for which we established a previously unrecognized role in (macro)colony morphology and biofilm formation. Additionally, we showed <em>Galleria mellonella</em> larva are susceptible to <em>Mk</em> infection, demonstrating the …
-
Sweet relief: regulating the response to glucose phosphate stress by the small RNA SgrS & Co.
… (i.e., phosphosugar stress) by producing a small RNA (sRNA) regulator, SgrS, which represses translation of sugar transporter mRNAs (ptsG and manXYZ) and enhances translation of a sugar phosphatase mRNA (yigL). Despite a molecular understanding of individual target regulation by SgrS, …
-
Fantastic ribonucleoprotein complexes and how to study them. Architectural principles of regulatory assemblies in bacteria.
The fate of a bacterial RNA transcript is controlled by three key players: ribonucleases, RNA binding proteins (RBPs) and small regulatory RNAs (sRNAs). Together these form an information-rich regulatory network that exercises post-transcriptional control of gene expression. A key RBP in bacteria …