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Showing 1 to 1 of 1 for “"Small interfering RNA--Synthesis."”.
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Chemical synthesis of glycosylated oligoribonucleotides for siRNA development
… methodology for the preparation of carbohydrate-RNA conjugates was established, which involved the use of 3,4~diethoxy-3-cyclobutene-l,2- dione (diethyl squarate) as the linking reagent. First, a glycan moiety containing an amino group reacted with diethyl squarate to form an activated glycan, …