Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Small heat shock proteins"”.
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The Gordian knot of small heat shock proteins and tissue transglutaminae
Contains fulltext : 32056_gordknofs.pdf (Publisher’s version ) (Open Access) Contains fulltext : 72514.pdf (Publisher’s version ) (Open Access)
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Disease-modifying effects of human small heat shock proteins in zebrafish models of neurodegeneration
… characterised by the build-up of misfolded proteins and degeneration of brain structures. Tauopathies are a collective of >20 such diseases featuring abnormally aggregating tau, a microtubule-associated protein normally acting to stabilise these protein cargo tracks. There is currently no …
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Subcellular and functional analyses of two small heat shock proteins and protein kinases from peroxisomes of Arabidopsis thaliana L.
… konnten zwei kleine Hitzeschockproteine (sHsps - small heat shock proteins) und sieben Proteinkinasen identifiziert werden. Die kleinen Hitzeschockproteine (AtHsp15.7 und AtAcd31.2), deren Homologe noch in keinem Organismus in Peroxisomen nachgewiesen worden waren, wurden mit Hilfe von …
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Degradation of the E. coli small heat-shock proteins by the AAA+ protease lon : significance to protein quality-control
… and elimination of damaged and aggregated proteins requires the concerted effort of several branches of the protein quality-control network. This network includes refolding chaperones, disaggregases, holdases and proteases. Many years of investigation have led to a partial understanding of …
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The Biological Basis for Toughness in Beef
The aim of this thesis was to elucidate role of small heat shock proteins (sHSPs) in the development of tenderness in beef. Data in this thesis were predominantly obtained from bull M. longissimus dorsi aged at -1.5°C for up to 28 days post mortem. High (pH ≥ 6.2) and low (≤ 5.79) ultimate pH (pHu) …
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Identification And Characterization Of Mediators Of Toxicity Of Aβ Oligomers By Genome Wide Screening In <i>Caenorhabditis Elegans</i>
… are poorly understood. In order to search for proteins involved in the formation and/or toxicity of Aβ oligomers, a transgenic <i>C. elegans</i> model of AD was used in which inducible expression of Aβ oligomers results in a complete paralysis; in these worms a genetic screen following chemical …
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Molecular interactions and their impact on life sciences
… study the binding and thermodynamics of small heat shock proteins, such as clusterin, αB-crystallin and the Brichos chaperone domain, to aggregated forms of amyloid-beta and α-synuclein, protein aggregates that are associated with a wide range of neurodegenerative diseases. The three …