Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"SmPill®"”.
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Investigation of the Efficacy of a Novel CsA Formulation Alone or in Combination with Cell Therapy in a Humanised Mouse Model of GvHD
… we have shown that a novel CsA formulation, SmPill® provided safe and superior efficacy in comparison to routinely used CsA drugs, Neoral® and Sandimmune® IV in a humanised model of aGvHD. We have shown this enhanced efficacy using pre-clinical survival studies, histopathology and cytokine …
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Design and evaluation of novel microencapsulation technologies to enhance delivery of Ciclosporin
… an alternative microencapsulation technology, SmPill® minispheres, to target CsA delivery to the colon. Characterisation of CsA release in vitro and in vivo was performed. By modulating the ethylcellulose:pectin coating thickness, release of CsA in-vivo was more effectively controlled compared …