Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 112 for “"Slim"”.
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Applications of SLIM (Spectral Localization by Imaging) localization technique
Because of the intrinsic inhomogeneity in the composition of living systems, applications of nuclear magnetic resonance spectroscopy (MRS) to the biological system require techniques that can discriminate signals according to their spatial origins and detect signals only from the …
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InsulPatch: A Slim, Powerless Microfluidic Patch-Pump for Insulin Delivery
… syringes and battery-powered pumps because it is slim, powerless, painless, and relatively inexpensive. The majority of this thesis focuses on the fabrication and testing of microfluidic devices for the delivery of insulin, which is a model drug that is widely used and needs to be delivered …
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Ehrlichia chaffeensis Activates Notch Signaling Through SLiM Mimicry to Inhibit Apoptosis
… of this research project is to identify the SLiM ligand mimetic in E. chaffeensis TRP120 and the functional implications of TRP120 Notch activation. Two aims were originally proposed to investigate this hypothesis. Aim 1 was to elucidate the molecular interactions required for TRP120 Notch …
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Slim chance : adult students' access to university-administered merit-based undergraduate scholarships
University-administered merit-based undergraduate scholarship awards have egalitarian appearances that often mask the presence of eligibility criteria that funnel these awards towards some students and away from others. This thesis uses findings from a case study to examine whether adult students …
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Numerical Modelling and Analysis on Structural Behaviour of Composite Slim-Floor Beams
… aims to investigate the behaviour of composite slim-floor beams based on numerical modeling and analysis. This dissertation summaries the developments and prospects of composite floor beams, includes investigation of push-out tests, shear beam tests, flexural beam tests. The most important …
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Thermo-economic optimation of slim power cycles : a case of Ngozi geothermal project-Tanzania
… this, a comparative thermo-economic analysis of slim wells against full size wells is done for a selection of power plant cycles. To obtain a realistic estimate of the wellbore output, as required for the thermo-economic analysis, well bore data from Pritchett [1] is used as basis for the …
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Analytical Hierarchy Process Evaluation of the Proposed Slim Modular Flexible Electric Bus Rapid Transit System
… is better functioning and more cost-effective. Slim Modular Flexible Electric Bus Rapid Transit (SMFe-BRT) has characteristics that are expected to reduce the initial construction and operation and maintenance costs. Also, it is expected to have higher operational flexibility. The thesis …
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Spatial light interference microscopy (slim) measurements of hypothermia in an experimental cellular model of traumatic brain injury
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms
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Quantitative phase imaging: advances to 3D imaging and applications to neuroscience
… First, spatial light interference microscopy (SLIM) is introduced as a QPI method extensively used in this thesis. Using this setup, an application of QPI in neuroscience is demonstrated by studying the emergent formation of a neuronal network. Second, an expansion of this QPI method into a 3D …
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Spatial light interference microscopy and applications
… I present spatial light interference microscopy (SLIM), a new optical method, capable of measuring optical path-length changes of 0.3 nm spatially (i.e. point to point change) and 0.03 nm temporally (i.e. frame to frame change). SLIM combines two classic ideas in light imaging: Zernike’s phase …
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Eukaryotic protein mimicry as an infection strategy for Ehrlichia chaffeensis
… to identify a repetitive short linear motif (SLiM) in TRP120 that is homologous to Wnt ligands and used mutant SLiM peptides and an α-TRP120-Wnt-SLiM antibody to demonstrate that the TRP120 Wnt SLiM activates the canonical Wnt pathway and promotes E. ch. infection. This document reports the …
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How short, degenerate motifs across the human proteome recognize the actin remodeling factor ENAH
… those that occur between short linear motifs (SLiMs) and structured domains. SLiMs are stretches of 3-10 residues found in intrinsically disordered regions of proteins. Given their degeneracy, short length, and weak affinities, it is not immediately clear how such low complexity interaction …
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Predicting motif mimicry in viruses
… a globular domain and a short linear motif (SLiM) in its partner. Advances in high-throughput experimental techniques have been applied at large-scale in an attempt to characterise the interactomes of various organisms. However, the PPI networks identified by these high-throughput experiments …
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Biochemistry of the uterus studied by magnetic resonance techniques
… techniques, Spectral Localization by IMaging (SLIM) and Diffusion-Weighted Imaging (DWI) in studies of uterine biochemistry. The work presented strives to: (1) investigate the relation between biochemical and structural heterogeneity in normal and abnormal uterus using high resolution …
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Exploring effective ways to implement strategic lean innovation management
… implement strategic lean innovation management (SLIM) to an organization from the perspective of cultural change, business strategies, and management tools and practices. Lean concepts focus on the reduction and identification of waste, variability, and cost while adding value to the customer. …
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Computational phase imaging for biomedical applications
… Spatial Light Interference Microscopy (tSLIM), that uses the twisted nematic liquid-crystal (TNLC) modulators. Compared to the established SLIM technique, tSLIM is much less expensive to build than its predecessor (SLIM) while maintaining significant performance. The tSLIM system uses …
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Developing a Contextual Annotation Framework for Short Linear Motifs in Proteins
Identifying and validating short linear motifs (SLiMs) is challenging due to their low sequence complexity and high prevalence across the proteome. Many false positives—sequences that match the pattern of the SLiM but are not involved in the biological functions typically associated with …
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Astroparticle physics with nuclear track detectors
… Monopoles, Nuclearites and Q-balls with the SLIM experiment at the Chacaltaya High Altitude Laboratory (5230 m, Bolivia), establishing upper limits (90% CL) in the absence of candidates, which are among the best if not the only one for all three kind of particles. A preliminary study of the …
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