Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 19 of 19 for “"Sleeping beauty"”.
-
The triumph of the (m)other : the feminine dichotomy in "Sleeping Beauty"
The tale of 'Sleeping Beauty' offers a familiar fairy tale narrative that features a beautiful sleeping princess, a wicked witch and a dashing prince who saves the day. This formulaic narrative has its roots in oral tales that date back to thousands of years ago. The fact that this narrative has …
-
Is Sleeping Beauty still slumbering?: An investigation of the feminist critique of modern romanticism
Feminists have articulated a critique of women's socialization in a culture of romance which suggests that women seek legitimation as persons through their relationships with men. This study outlines women's socialization in romance as well as the feminist critique, and then investigates …
-
Sickle Cell Disease: The Role of the Non-Viral Sleeping Beauty Transposon System Driven by the IHK Promoter in Inducing Sustained ?-globin expression and a Model Case Study
… literature review that discusses the use of the Sleeping Beauty transposon system under the control of various molecular mechanisms to promote normal ?-globin protein expression. The specifics of these mechanisms, most notably the use of the IHK promoter, are further elucidated through …
-
Science of science: Biological research network
… research. On a global scale, we try to predict sleeping beauty species that may become important in the future despite not being popular at present and try to predict what pairings of species may be influential in biology.
-
Fairy Tales: The Dark Side
… partner violence. Different versions of the “Sleeping Beauty” fairy tale provided insight into the issue of sexual assault. Additional research involved examining the work of feminist artists who used fairy tales for inspiration, for instance, Kiki Smith, Paula Rego, and Sally Smart. Jones’ …
-
Revising identification: fairy tales that transform tradition from within
… of four classic fairy tales: “Snow White,” “Sleeping Beauty,” “Little Red Riding Hood,” and “Bluebeard,” drawing on José Esteban Muñoz’s concept of “disidentification” to describe the revisionary work they perform. Muñoz provides a model of subversion that illuminates the work done in these …
-
All done by mirrors: reflectivity in the novels of Elizabeth Taylor (1912-75)
… " A Game Of Hide And Seek (1951) and The Sleeping Beauty are interrelated with the Grimm fairy tale. Two major characters in Angel (1957) and The Wedding Group (1968) are shown to be based on real people and their psychology to define one theme. Two Henry James novels are detected as the …
-
Septimius Felton: Hawthorne's Last Novel
… <em>Septimius</em> has been put aside, a Sleeping Beauty of the library archives forest.</p> <p>But unlike the majority of learned Critic-princes, I felt <em>Septimius Felton</em> deserved to be awakened and presented to the reading public. Spurred on by the fascination it held for me, I …
-
"You" and "I", "now" and "then", and some related thoughts
… intuitions about a well-known example, the Sleeping Beauty problem, with an intuitively plausible principle about context-dependent information, the Relevance-Limiting Thesis.
-
'Little Red Riding Hood' in the 21st Century: adaptation, archetypes, and the appropriation of a fairy tale
… tale sisters such as Snow White, Cinderella, Sleeping Beauty et al, thus allowing for so many diverse portrayals of her character: as the child, the innocent victim, the femme-fatale, and the monstrous feminine. The rationale behind the thesis is threefold; firstly, ‘Little Red Riding Hood’ is …
-
The Rise of Romantasy: Female Desire, Monstrous Feminists, Fairy Tale Ideology, and Societal Panic
… traditions such as “Little Red Riding Hood,” “Sleeping Beauty,” and “Beauty and the Beast”, and Sarah J. Maas's <em>A Court of Thorns and Roses</em>, I demonstrate how narratives centered on women's maturation and desire have historically served as ideological training grounds. In many horror …
-
Employing T Cells For Antigen Presentation: Role of Ny-Eso-1+ T-Apc Vaccine In Multiple Myeloma
… and Methods</strong>: Using the Sleeping Beauty transposon/transposase system, an NY-ESO-1<sup>+</sup> TCR and CAR were created as effector cells. Vaccine was produced by electroporation of the NY-ESO-1 gene into T cells to make T cell antigen presenting cells (T-APC). …
-
Novel Approaches to Transgenesis in the Teleost Medaka (Oryzias latipes)
… approach using the artificially reconstructed Sleeping Beauty (SB) transposon was established. To address the potential of SB for transgenesis, microinjection experiments were performed. Transgenes (GFP) and promoter fragments were flanked with the SB recognition sequences (inverted direct …
-
Targeting An Ancient Retrovirus During Melanoma Using Adoptive T Cells Therapy
… new CAR was cloned as a transposon into our <em>Sleeping Beauty</em> (SB) system that we have adapted for human application. DNA plasmids coding for the HERV-K env-specific CAR and SB transposase were electro-transferred into primary human T cells, and genetically modified CAR<sup>+</sup> T cells …
-
Creation of Versatile Cloning Platforms for Transgene Expression and Epigenome Editing and Their Application to Pancreatic Islet Biology
… adenovirus, expression plasmid, lentivirus, and Sleeping Beauty transposon, thus, permitting the creation of > 8000 unique vector permutations. Multiple features of this new vector platform, including cell type-specific and inducible control of gene expression, were validated in the setting of …
-
TRANSLATIONAL RESEARCH TARGETING BILIARY TRACT CANCER
… targeting tumor suppressor genes are encoded in Sleeping Beauty (SB) transposon plasmids, which are permanently delivered via integration into liver cell genomes. Mice were also treated with the liver injury agent Diethyldithiocarbamate (DDC) for 4 weeks to expedite the development of CCA. To …
-
Insights into determinants of cancer susceptibility, initiation, and progression:studies on medulloblastoma and Histiocytic Sarcoma in mouse models
This dissertation presents a discussion of both perigestational dietary influence on cancer predisposition as well as somatic genetic determinants of cancer development. Both projects used genetically engineered mouse models of cancer. The introductory chapter gives a brief historical introduction …
-
Redirecting T Cells With Chimeric Antigen Receptors to Target Cd123+ Leukemia
… em><em>ee</em><em>p</em><em>i</em><em>n</em><em>g Beauty</em> (SB) was employed as a non-viral gene transfer s ystem to stably express 2<sup>nd</sup> generation CARs in T cells derived from peripheral blood mononuclear cells (PBMC). The CARs were co-expressed with inducible Caspase 9 (iCaspase9) …
-
ANALYSIS OF HERPES SIMPLEX VIRUS ICP0 FUNCTION AND THE ANTIBODY RESPONSE TO A LIVE HSV-2 ICP0- MUTANT VACCINE
… Vero cell lines using a system that relies on Sleeping Beauty transposase to introduce two genetic elements into the chromosomes of target cells: 1. a Tet-regulatable gene-of-interest driven by the VP16- inducible HSV-1 ICP0 promoter and 2. a highly expressed bicistronic gene that expresses the …