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Showing 1 to 1 of 1 for “"Sleeping Beauty System"”.
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Redirecting T Cells With Chimeric Antigen Receptors to Target Cd123+ Leukemia
… em><em>ee</em><em>p</em><em>i</em><em>n</em><em>g Beauty</em> (SB) was employed as a non-viral gene transfer s ystem to stably express 2<sup>nd</sup> generation CARs in T cells derived from peripheral blood mononuclear cells (PBMC). The CARs were co-expressed with inducible Caspase 9 (iCaspase9) …