Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"Sleep-wake cycle"”.
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A Mathematical Model of the Sleep-Wake Cycle
The daily sleep-wake cycle usually consists of three distinct states: wakefulness, non-rapid-eye-movement (NREM) and rapid-eye-movement (REM). The process of switching between different states is complex, but a common assumption is that it is regulated primarily by two processes (the circadian and …
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Sleep-wake Cycle Assessment in Type 2 Diabetes and Salivary Melatonin Correlates
… before bed time and latency (Ï=-.87; p=.001), wake after sleep onset (Ï =-.69; p=.02) and nocturnal activity (Ï =-.67; p=.03). Latency was inversely correlated with melatonin collected at bed time (Ï =-.69; p=.02). These findings suggest that T2DM presents disturbances in the homeostatic and …
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Regulation of dorsal raphe serotonergic neurons by histamine
Neural control of the sleep-wake cycle results from the complex interaction of neurotransmitters systems, which arise from anatomically and chemically defined brain structures. Serotonergic neurons located in the dorsal raphe nucleus (DRN) are currently accepted to be wake-promoting however their …
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Regulation of Circadian Rhythms by Sleep -Wake Centers in the Brainstem and Basal Forebrain
… in phenomenon including hormone release and the sleep-wake cycle, and in mammals are regulated by the suprachiasmatic nucleus (SCN). The proper interaction of the circadian and sleep-wake cycles is essential for well-being, but the means by which these processes interact is unknown. The nucleus …
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Studio dei ritmi circadiani in pazienti in stato vegetativo
Objective: To study circadian rhythms (sleep-wake, body core temperature and melatonin circadian rhythms) in patients in vegetative state (VS) in basal condition and after nocturnal blue light exposure. Methods: Eight patients in VS underwent two experimental sessions of 48 consecutive hours …
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Characterization of the genetic variability of human arylalklamine-N-acetyltransferase (AA-NAT) and its potential effects on melatonin production and the sleep pattern
The human sleep/wake cycle is characterized by a circadian rhythm of circulating melatonin levels, which has been attributed to the cyclic expression of its biosynthetic rate-limiting enzyme, arylalkylamine-N-acetyl-transferase (AA-NAT). Genetic variability of the AA-NAT gene may therefore …
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The Effect of Increased Sleep on the Circadian Rhythm of Salivary Cortisol Concentrations
… a circadian rhythm. It is well known that sleep deprivation increases cortisol concentrations. In this study, we looked at the effect of an increase of one-hour sleep for one month on the circadian rhythm of the HPA.</p> <p>Eight college subjects (n=8) collected saliva during their normal …
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Investigation of hypothalamic molecular mechanisms underlying narcolepsy and obesity through DNMT1 and leptin receptor signalling
Sleep disorders and obesity are common diseases that can reduce the length or quality of life for millions of people. These diseases result in part from the dysfunction of cell populations in the hypothalamus that regulate the sleep/wake cycle and energy balance, respectively. There has been …
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Flexible Smart Sensor Framework for Autonomous Full-Scale Structural Health Monitoring
… Flexible network management software combines a sleep/wake cycle for enhanced power efficiency with threshold detection for triggering network wide operations such as synchronized sensing or decentralized modal analysis. A cable-stayed bridge in South Korea serves as one of the test beds for this …
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Characterizing cerebellin-short, a novel circadian peptide, in the rat suprachiasmatic nucleus
… such as metabolism, hormone release, and the sleep/wake cycle, are orchestrated by the suprachiasmatic nucleus (SCN) located in the hypothalamus. Mass spectrometry peptidomics of the SCN identified the small peptide cerebellin-short (SGSAKBSAIRSTN) consisting of 15 amino acids, which is …
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Analysis and detection of driver fatigue caused by sleep deprivation
… alertness based on driver-vehicle data. Although sleep and fatigue are major causes of impaired driving, neither effective regulations nor acceptable countermeasures are available yet. The first part of this thesis analyzes driver-vehicle systems with discrete sleep-deprivation levels, and reveals …
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Incubating dreams : awakening creativity
… of our minds. The dreaming experience at sleep onset, called hypnagogia, is the main focus of this thesis: these first minutes of sleep provide ideal conditions for incubating specific dream content and recalling it after awakening. This thesis presents Dormio, an interactive system which …
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Early detection of delirium in older medical inpatients: prodrome, predictors and motor subtyping
… in the prodrome (for example inattention; and sleep-wake cycle disturbance). Examining longitudinal motor subtypes in delirium cases, subtypes were found to be predominantly stable over time, the most prevalent being hypoactive subtype (62.3%). Discussion This thesis explored multiple aspects …
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Investigating state-dependent pontine cholinergic activity during REM sleep and P-waves in vivo
Rapid eye movement (REM) sleep is a behavioural state during which phasic deflections in pontine LFP, known as pontine waves (P-waves), occur most prominently. Cholinergic pedunculopontine and laterodorsal tegmental nucleus (PPT/LDT) neurons have been implicated in the generation mechanisms of both …
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The Application and Challenges of RNA-Sequencing to the Study of Circadian Rhythms
… most ancient selective pressures; the day-night cycle. Mounting evidence suggests the clock plays important roles in critical metabolic and signalling pathways, the sleep/wake cycle, immune function, as well as learning and memory. Perhaps more importantly, misregulation of the clock is …
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STUDIO DEL RUOLO DELLA PROTEINA PRIONICA NELLA REGOLAZIONE DEL SONNO MEDIANTE L'UTILIZZO DI MODELLI MURINI TRANSGENICI
… electroencephalographic alterations but recently sleep modification have been described. Moreover a role for PrP in sleep has been proposed on the basis of data collected in Knock-out mice. We generated a new mouse model of CJD (Tg(CJD)) that express the murine homologue of the D178N/V129 human …
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Percepção do estresse acadêmico, padrões de sono e desfechos em saúde mental em estudantes do ensino médio no turno matutino
… is marked by physiological changes in the sleep-wake cycle, in which individuals sleep and wake up later. In contrast, schools often start classes very early in the morning, leading to daytime sleepiness, concentration difficulties, and worse cognitive processing. In this context, …
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Qualidade do sono, sonolência diurna e fatores associados em estudantes universitários: um estudo baseado nos determinantes sociais
… emergence of unhealthy habits and changes in the sleep / wake cycle (CSV). These changes in CSV can have consequences on the physical, mental and social health of these young people. In addition, the living conditions of individuals and population groups can also be considered risk factors for the …
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Characterising hippocampal replay in the APP<sup>NL-G-F</sup> mouse model of Alzheimer’s disease
… and predominantly occurs during rest and sleep. More generally replay is also held to play a role in memory retrieval, navigation, and likely planning. Consistent with these multiple roles, replay disruption negatively impacts performance on memory related tasks. The hippocampus and …
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Distúrbios do sono na população brasileira: análise dos fatores associados às queixas de redução da função reparadora do sono, insônia, sonolência e suas implicações em morte e eventos cardio-cerebrovasculares
Sleep disturbances are characterized by changes in the sleep-wake cycle. Studies on sleep conditions and their repercussions on the Brazilian population are mostly in the clinical context, reducing the impact of the findings. The aim was to identify biological/health, behavioral and social factors …
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