Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Skin permeation"”.
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Effect of formulation factors on the skin penetration of drugs
Permeation of chemicals through skin can lead to systemic effects of drugs or toxic exogenous chemicals. Skin permeation of compounds and the effect of mixture ingredients can be related to their chemical structures as expressed by molecular properties. This approach, known as Quantitative …
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Experimental and theoretical investigation of the effects of low-frequency sonophoresis on transdermal drug transport
… first-pass effects. However, due to the low skin permeability, transdermal drug delivery is currently limited to only a handful of drugs that are hydrophobic and of low molecular weight. The pharmaceutical relevance of many molecules that are excluded from this category, such as proteins, …
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A novel encapsulation favorably modifies the skin disposition of topically-applied N,N-diethyl-3-methylbenzamide (DEET)
The skin disposition of the insect repellent N,N-diethyl-3-methylbenzamide (DEET) was modified using a unique encapsulation method. Incorporation of DEET into a controlled-release microcapsule facilitated a decrease in skin absorption compared to a DEET in ethanol control while evaporation rates …
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SELECTION OF TARGETING MOIETIES DRIVING NANOPARTICLE PENETRATION THROUGH SQUAMOUS PLURISTRATIFIED EPITHELIA
… through these kinds of epithelia, like the skin, the esophageal membrane, and the corneal membrane, poses significant challenges due to their complex structure and barrier properties restricting drug absorption. Therefore, overcoming these barriers requires innovative approaches tailored to …
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A stability study of dithranol in solution, formulations and in normal and psoriatic skin.
… solution and that of decomposition/metabolism in skin stability studies were carried out in aqueous buffer (PH 5.5). The effect of various factors such as the presence of various metal ions and surfactants on the decomposition pattern (individual rates of dimer and danthron formation) of dithranol …