Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 29 for “"Skin model"”.
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3D in vitro skin model as broadly available multipurpose platform
L'abstract è presente nell'allegato / the abstract is in the attachment
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Antimicrobial Inhibitory Activities of Phenolic Extracts from Four Selected Soybean Hulls in Culture and Chicken Skin Model Systems, and Preliminary ACE-Inhibitory Activity
… and Campylobacter jejuni attached to chicken skin, and 4) Investigated the ACE-I inhibitory activity of the soybean hull phenolic extracts. The highest phenolic content was observed in R07-1927, the darkest colored soybean hull (4.29 mg CAE/g DW), and was found to be significantly different …
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The use of in vitro 2d co-culture models to determine the optimal keratinocyte: melanocyte ratio to be used in the development of pigmented 3d skin model
… for instance the use of various forms of skin auto-grafts. Despite such great success with all kinds of innovative ideas surrounding the use of autologous skin grafting, lack of available donor sites for skin grafts still remains a problem, more so in cases where patients suffer burns …
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Microneedle array patches for skin hyperthermia and enhanced intradermal drug delivery
… between 50 μm and 2 mm. When applied to the skin surface, they pierce the stratum corneum creating micropores that can enhance the delivery of drugs into the viable skin layers. MN arrays offer great advantages for localised treatment of skin disorders which, in combination with skin …
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Effects of a Plant Extract Mixture on Atopic Dermatitis and Psoriasis and their Underlying Mechanisms
… worldwide suffer from chronic inflammatory skin diseases. Atopic dermatitis (AD), characterized by itchy eczematous lesions, is particularly prevalent. Another common condition is psoriasis, which is characterized by strongly scaly, painful skin lesions. There is still a high demand for …
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Human skin optical properties and autofluorescence decay dynamics
Human skin is an optical organ which constantly interacts with light. Its optical properties are fundamental to understanding various effects of light-tissue interaction inhuman skin and to laser applications in medicine and biology. The aim of this thesis was to test two hypotheses: (1) that skin …
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Digital Image Processing via Combination of Low-Level and High-Level Approaches.
… obtain the final new edge. In Face Detection, a skin model is built first, then the boundary condition of this skin model can be extracted to cover almost all of the skin pixels. After skin detection, the knowledge about size, size ratio, locations of ears and mouth is used to recognise the face …
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From Waves to Touch: Advancing Ultrasound Haptics through Novel Modulation
… (AM and STM) can elicit sensations in the human skin for 2D shapes, there is still much to be desired in terms of spatial precision for high-speed scanning points. Specifically, when points are scanned across the human palm at speeds greater than the shear speed of sound, a trailing Mach cone is …
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Influence of transdermal current flow in tDCS-induced cutaneous adverse events
… 1) the relationship between tDCS-induced skin reddening (erythema) profile and local current density profile predicted by the model; 2) the source of burning sensation during tDCS and whether it is related to an actual skin heating; 3) the role of skin multi-layers and ultrastructures …
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Tissue engineering of co-cultured skin substitutes using biocomposite membranes based on collagen and polycaprolactone
… for manufacture of tissue engineered skin substitutes are reported. Films of collagen: PLC, gelatin: PCL (1:4, 1:8 and 1:20 w/w) and gelatin/collagen:PCL (1:8 and 1:20 w/w) biocomposites were prepared by impregnation of lyophilised collagen and/or gelatin mats by PCL solutions followed …
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Conformable Ultrasound Face Patch for Cavitation-enhanced Transdermal Cosmeceutical Delivery
Increased consumer interest in healthy-looking skin demands a safe and effective method to increase transdermal absorption of innovative therapeutic cosmeceuticals. However, permeation of small-molecule drugs is limited by the innate barrier function of the stratum corneum. In this thesis, we …
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Exploiting Chemical Libraries to Identify and Characterize Novel Bioactives with Efficacy Against Pathogenic Candida Species
… assess the efficacy of this molecule in a mouse skin model of dermatomycosis. Finally, I engaged in a collaborative program to optimize inhibitors of the fungal casein kinase, Yck2. An existing Yck2 inhibitor, GW, was rationally modified to generate substituted analogues and …
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Reflectance spectroscopy system for real time and non-invasive detection of transcutaneous bilirubin level
… of using Modified Lambeti Beer (MLB) A model in the prediction of one's bilirubin concentration using a priori knowledge of the extinction coefficient of bilirubin and haemoglobin components in the wavelength range of 400 500 nm. This study verified validity of the predicted value using …
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Effect of stressed skin action on the behaviour of cold-formed steel portal frames with non-linear flexible joints and top-hat purlins
… the effects of joint flexibility and stressed skin diaphragm action. The frames used for the laboratory tests were of 6m span, 3m height, 10° pitch and the frame spacing was 3 m. When the difference in loads between 2D (bare frame model) and 3D (stressed skin model) were considered, it was …
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Control of broadband acoustic radiation from structures using a piezoelectric double-amplifier active-skin
In this work, the potential of an active-skin is demonstrated for the reduction of broadband acoustic radiation from a vibrating structure. A simplified representation of the active-skin, employing acoustic monopoles as secondary sources, is explored as a precursor to the more complicated analyses …
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Preclinical evaluation of dissolvable microarray patches for allergy treatment: key factors governing in vitro and in silico assessment
… metabolism and unpredictable pharmacokinetics. Skin delivery represents a promising alternative, with innovative platforms such as dissolvable microarray patches (MAP), offering the potential for targeted local and systemic drug effects. However, no dissolvable MAP have yet reached the market. …
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Controlled Surface Layer Deposition for Steel Surface Hardening
… at all temperatures. A tentative Onion Skin model was used to explain the cross-sectional phase distribution in the coating of the samples. A thermal expansion mismatch model was used to describe coating delamination and vertical crack formation, propagation, and branching. The optimal …
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Experiences concerning the development of identities of primary school physical education specialist teachers during the first year of teaching in England. A phenomenological case study
… examines the findings uses Korthagen’s Onion Skin Model (2004) of values and belief and Lawson’s model of Teacher Socialisation (1983a; 1983b, 1986). In contrast to much of the preceding literature this study provides detailed empirical work on identity development from the perspective of …
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Optimal Control of Thermal Damage to Biological Materials
… planning refers to the use of computational models to optimize the heating protocol to be used in a hyperthermia treatment. This thesis presents a method to optimize a hyperthermia treatment heating protocol. An algorithm is developed which recovers a heating protocol that will cause a …
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Innovative Structural and Mechanical Satellite Systems
… The second topic covered is the electromagnetics modeling and simulation of inductive spin drive for a novel magnetically levitated spherical control moment gyroscope for satellite attutide control. For the first topic on BeaverCube 2, the key tasks were to design and assemble the structure of the …
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