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Showing 1 to 3 of 3 for “"Ski7"”.
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Functions of Dcp2 and Ski7 In Mrna Degradation
… exosome and its cofactors, the Ski complex and Ski7, are required for degradation of nonstop mRNAs. While Ski7 is known to have nonstop decay specific function, its exact role in nonstop decay remains unknown. Moreover, whether Ski7-mediated nonstop mRNA decay is mechanistically linked to the …
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Evolution Via Gene Duplication and Alternative Splicing In The Eukaryotic Ski7 and Hbs1 Genes
… Here I study these phenomena for the <em>SKI7</em> and <em>HBS1</em> gene pair. These <em>Saccharomyces cerevisiae</em> genes were created as part of a whole genome duplication (WGD) event and have since functionally diverged. Although both genes function in mRNA surveillance pathways, the …
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Genetic Analysis of Rna Exosome Complex Cofactors
… complex, which functions to degrade mRNA, binds Ski7 and the SKI complex, which comprises Ski3, Ski8 and the cytoplasmic RNA helicase, Ski2. In the nuclear RNA exosome complex Rrp6 has both catalytic and structural roles in that it mediates the interaction of the RNA exosome complex to other …