Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Skeletal malformation"”.
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High Saturated Fat Diet Induces Gestational Diabetes, Perinatal Skeletal Malformation and Adult-Onset Chronic Diseases
… has been linked to increased risk of musculoskeletal, cardiovascular, and metabolic diseases; however, the contribution of gestational HFD to elevated oxidative stress (OS), perinatal cardiovascular, skeletal, and metabolic dysfunction as well as long-term effects on adult offspring are …
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Delineating the molecular mechanisms regulating chondrogenesis
… Haploinsufficiency of Sox9 in humans leads to a skeletal malformation syndrome known as campomelic dysplasia. To understand the regulation of Sox9 during chondrogenesis, the developing mouse limb was used to identify and characterize regulatory regions within the Sox9 promoter. Luciferase-based …
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Developmental Malformations in Zebrafish Caused by Exposure to Environmental Pollutants
… environmental chemicals causing congenital malformations. High-throughput screening of 292 unique chemicals from the ToxCast Phase I library identified 38 skeletal disruptor compounds (SDCs) producing bone and craniofacial cartilage malformations in zebrafish. We used ToxCast in vitro data …