Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Skeletal disease"”.
-
The Effect of Lycii Radicis Cortex Extract on Bone Formation in vitro and in vivo
Osteoporosis is a common skeletal disease. It is caused by decreased bone mass and enhances the risk of bone fracture. In this study, I aimed to discover novel herbal extract(s) for the treatment of osteoporosis. I screened 64 ethanol extracts of edible plants native to Korea for their ability to …
-
Effects of Estrogen Loss on the Vascular Porosity in Rat Cortical Bone
"Osteoporosis is a skeletal disease that currently affects 10 million Americans, and is characterized by low bone mass and increased skeletal fragility (National Osteoporosis Foundation, 2011). Estrogen loss, which begins during menopause, is the leading cause of osteoporosis in women. Recent …
-
Age and Gender Effects on Strain Response and Biomechanical Performance of C57BL/6 Mice
Osteoporosis is a systemic skeletal disease resulting in low bone mass and micro architectural deterioration of bone tissue. It causes a consequent increase in bone fragility and susceptibility to fracture. This age-related bone loss is a major healthcare problem nowadays. Due to this fact, ability …
-
Combination of Dasatinib and Dexamethasone targets the myeloma plasma cell through its interaction with the bone marrow microenvironment
… all patients eventually relapse with progressive disease. Cell adhesion mediated drug resistance and a permissive bone marrow microenvironment facilitates myeloma cell survival. Upto 90% of myeloma patients present with bone disease of varying degrees, which is a result of enhanced osteoclastic …
-
Role of the RUNX2 rs59983488 variant in bone mass determination and fracture risk in Malta
Osteoporosis is a multifactorial skeletal disease which is characterised by a reduced bone density (BMD) and compromised bone microarchitecture, leading to an increased fragility fracture risk. The Runt-related Transcription Factor 2 (RUNX2) protein encoded by the RUNX2 gene is involved in the …
-
Automated Modelling of Cortical Bone from Clinical CT
Osteoporosis is an age-related skeletal disease characterised by an increased incidence of fragility fractures. In this thesis I develop a new technique capable of measuring the thickness of the previously unmeasured endocortical region, and providing an improved measure of the cortical bone …
-
The Role of Annexin A6 in Osteoporosis
Osteoporosis is a common calcium and metabolic skeletal disease which is characterized by decreased bone mass, microarchitectural deterioration of bone tissue and impaired bone strength, thereby leading to enhanced risk of bone fragility. In this study, we aimed to discover a novel herbal …
-
Correlation of Osteoporosis and Obesity
Osteoporosis and obesity are two complex diseases that are prevalent in the United States. Obesity is a condition of excess body fat that exacerbates several major public health problems. Osteoporosis is a skeletal disease characterized by a reduction in bone mass. The relationship between obesity …