Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Skeletal Muscle Physiology"”.
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NOVEL ROLES FOR GRK2 IN METABOLIC HOMEOSTASIS AND SKELETAL MUSCLE PHYSIOLOGY
… protein-coupled receptor kinase 2 (GRK2) in the physiology and pathophysiology of the heart. Adrenergic receptors are the primary target for GRK2 activity in the heart; phosphorylation by GRK2 leads to desensitization of these receptors. As such, levels of GRK2 activity in the heart directly …
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Understanding adaptive regulation of skeletal muscle physiology in the Weddell seal: a proteomics approach
… adults. Proteins from the primary swimming muscle (M. longissimus dorsi) of two distinct age classes, pups (3-5 weeks/nondivers) and adults (7+ years/expert divers), were visualized using two dimensional gel electrophoresis (2DE), quantified, and identified. This study validated the use of …
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Aerobic Exercise-Mediated Prevention Against Glucocorticoid Myopathy in Aged Skeletal Muscle
… adults are vulnerable to glucocorticoid-induced muscle atrophy and weakness, with sex potentially influencing susceptibility to those effects. Aerobic exercise can reduce glucocorticoid-induced muscle atrophy in young rodents. However, it is unknown whether aerobic exercise can antagonize …
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Oxygen Generating Materials for Tissue Restoration and Regeneration
Traumatic injury to skeletal muscle produces a physiological deficit resulting in deterioration of tissue structure and function. The restoration or regeneration (i.e., tissue engineering) technologies required to effectively treat these injuries would benefit from provision of oxygen in situations …
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Force potentiation as a modulator of contractile performance: Implications for control of skeletal muscle force and energetics of work
… contractile function during ramp shortening, and muscles were frozen during parallel incubations for biochemical analysis. The central feature of this research was the comparison of fast hindlimb muscles from wildtype and skeletal myosin light chain kinase knockout (skMLCK-/-) mice that does not …
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THE ROLE of THE CIRCADIAN CLOCK IN DISEASE and TISSUE FUNCTION
… tissue-specific gene expression and downstream physiology. The central pacemaker located in the hypothalamic suprachiasmatic nuclei (SCN) synchronizes the peripheral clocks in different tissues. This dissertation aims to uncover specific circadian regulatory mechanisms in the brain and skeletal …