Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Sirtuin 2"”.
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Bioinformatik-Strategien zur Analyse regulatorischer RNA-Motive und ihre experimentelle Validierung
… Rab1A 3'UTRs verschiedener Vertebraten und der Sirtuin 2[alpha] 3'UTR von Mensch und Maus vorkommt. Experimentelle Analysen im Rahmen der vorliegenden Arbeit konnten Hinweise auf eine biologische Funktion des vorhergesagten Stemloops in der Rab1A 3'UTR liefern. Die Ergebnisse von …
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Regulation of AMPA receptor acetylation and translation by SIRT2 and AMPK: the molecular mechanisms and implications in memory formation
… protein kinase (AMPK) and sirtuin 2 (SIRT2), are described. It is shown that SIRT2, a NAD+-dependent protein deacetylase, directly controls AMPAR stability by regulating AMPAR acetylation. For the first time, we discovered that AMPARs are subject to lysine acetylation, a …
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Regulation of polarised trafficking by Klp98A
… two enzymes, p-21 activated kinase 1 (Pak1) and Sirtuin 2 (Sirt2), resulted in symmetric endosome segregation despite an asymmetric landscape of microtubule tracks. In the case of Pak1, this endosomal phenotype appeared to arise due to a delay in the targeting of endosomes to the central spindle, …