Global ETD Search

Role of dendritic cells in response to cytokine gene adjuvants

Matthews, KatieThe University of Edinburgh2006

… isolated based on differential expression of SIRPa as described in both cattle and rats. Ovine SIRPa+ ALDC constitutively express high levels of IL-ip, IL-18 and IL-10 mRNA. Conversely, SIRPa ALDC do not express IL-10 but express high levels of IL-12p40. SIRPa+ ALDC may contain Langerhans' …

edinburgh Repository record for Role of dendritic cells in response to cytokine gene adjuvants (opens in a new tab)

Klonierung und Charakterisierung von Signal Regulatory Protein beta in primären Makrophagen der Maus

Spannagel, RalfUniversität Heidelberg

… exprimiert. Sie werden in 2 Gruppen, SIRPa und SIRPb unterteilt. Vertreter der SIRPa besitzen alle eine intracytoplasmatische Domäne, welche zwei �Immunoreceptor Tyrosin Based Inhibition Motifs� (ITIM) trägt und damit zur Klasse der In-hibitorischen Rezeptoren gehört. Vertreter der …

heid-diss Repository record for Klonierung und Charakterisierung von Signal Regulatory Protein beta in primären Makrophagen der Maus (opens in a new tab)

Refraktions- und Topografieänderungen der gesunden Kaninchenhornhaut nach Mikrotrepanation

Kompa, SirpaShaker1999

aachen Repository record for Refraktions- und Topografieänderungen der gesunden Kaninchenhornhaut nach Mikrotrepanation (opens in a new tab)

Mikrotuma-analyysi aneuploidogeenien tutkimisessa : Vinblastiinin vaikutus mikrotumien muodostumiseen ennen fytohemagglutiniinistimulaatiota ja sen jälkeen käsitellyissä ihmisen lymfosyyttiviljelmissä

Luomahaara, SirpaUniversity of Helsinki1992

helsinki Repository record for Mikrotuma-analyysi aneuploidogeenien tutkimisessa : Vinblastiinin vaikutus mikrotumien muodostumiseen ennen fytohemagglutiniinistimulaatiota ja sen jälkeen käsitellyissä ihmisen lymfosyyttiviljelmissä (opens in a new tab)

Deciphering pre-leukaemic dysregulation caused by mutant C/EBPα at the level of the single cell

Qureshi, MoosaUniversity of Cambridge2020

… identify a set of candidate genes (NOTCH2, JAK2, SIRPA, FOS, and others) where gene expression changes were associated with direct binding events by the mutant TF. In addition to characterising the transcriptional effects of the CEBPA mutation, a fourth objective was to update and expand the …

cambridge Repository record for Deciphering pre-leukaemic dysregulation caused by mutant C/EBPα at the level of the single cell (opens in a new tab)

Modelling functions from sample data with classification applications

Saarinen, Sirpa HelenaUniversity of Illinois at Urbana-Champaign2011

In this thesis we investigate various aspects of the pattern recognition problem solving process. Pattern recognition can be viewed as a decision making process where the underlying density functions or discriminant functions of the application have to be estimated often in a high dimensional …

uiuc Repository record for Modelling functions from sample data with classification applications (opens in a new tab)

Identification of tumour microenvironment-derived signals that modulate the development and functionality of MDSCs

Zimarino, CarloUniversity of Cambridge2021

Myeloid Derived Suppressor Cells (MDSCs) are a heterogeneous immune population found within the tumour microenvironment (TME). We sought to explore the potential role of microenvironment components on the suppressive behaviour, development and maintenance of MDSCs, focusing mainly on the role of …

cambridge Repository record for Identification of tumour microenvironment-derived signals that modulate the development and functionality of MDSCs (opens in a new tab)

Identification of homozygous deletion in ACAN and other candidate variants in familial classical Hodgkin lymphoma by exome sequencing

Ristolainen, Heikki, Kilpivaara, Outi, Kamper, Peter, Taskinen, Minna, Saarinen, Silva, Leppä, Sirpa, d'Amore, Francesco, Aaltonen, Lauri A.Helsingfors universitet2015

Tutkimuksessamme tarkastelimme Lähi-idästä lähtöisin olevaa perhettä, jossa kolmella viidestä lapsesta on todettu nuorellä iällä klassinen Hodgkinin lymfooma (cHL). Perinnöllinen alttius cHL:lle tunnetaan huonosti, eikä taudille mahdollisesti altistavia geenimuutoksia ole aiemmin raportoitui kuin …

helsinki Repository record for Identification of homozygous deletion in ACAN and other candidate variants in familial classical Hodgkin lymphoma by exome sequencing (opens in a new tab)