Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Single-strand conformation polymorphism"”.
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Population Genetics Analysis of the Grass Shrimp Palaemonetes Pugio Using Single Strand Conformation Polymorphism
… shrimp DNA was extracted and scanned using single stand conformation polymorphism. Results revealed P. pugio populations are highly conserved among localities. This suggests a significant amount of gene flow is taking place. Results also indicate there is no correlation between the most …
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The development of the single-strand conformation polymorphism (SSCP) technique to assess sequence level variation within the major histocompatibility complex (MHC) DRB1 gene in four South African buffalo (Syncerus caffer) populations
This thesis reports the development of Single-Strand Conformation Polymorphism (SSCP) technique to assess sequence level variation within the Major Histocompatibility Complex (MHC) DRB1 gene in four South African buffalo populations. MHC gene products are involved in the immune response, and so …
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Ecotoxicological and genetic effects of a mixture of heavy metals on selected aquatic macroinvertebrates
… by polymerase chain reaction and analyzed by single strand conformation polymorphism analysis to determine haplotype. Haplotype diversity was generally lower immediately following spring runoff than in late summer, and generally lowest at the most contaminated site. Haplotype diversity was …
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Identification and Characterization of Mitochondrial DNA Variants in Alzheimer's Disease
… the mitochondrially encoded COX subunits by single strand conformation polymorphism (SSCP) and DNA sequencing and identified thirty two variants. SSCP efficiency was estimated at 80%. Sixteen of the mutations are new mtDNA variants including a moderately conserved phe- $>$ leu missense change …
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Studies of the PTEN tumour suppressor in endometrial cancer.
… extracted DNA and the fragments separated by single-strand conformation polymorphism (SSCP) analysis. A number of samples exhibiting bandshifts were detected in both exons.
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Δημιουργία τράπεζας πληροφοριών Ελλήνων παρκινσονικών και εύρεση νέων και γνωστών μεταλλάξεων του γονιδίου NR4A2 και η λειτουργική τους σημασία
… και μάρτυρες της Τράπεζας με τη μέθοδο SSCP (Single-Strand Conformation Polymorphism) ανακαλύφθηκε μια καινούργια μετάλλαξη στο πρώτο εξώνιο (θέση που εντοπίζονται οι 4 από τις 5 γνωστές μεταλλάξεις του Nurr1) στη θέση -339 ενώ δεν εντοπίστηκαν στον υπό εξέταση πληθυσμό καμία από της ήδη 5 …
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Molecular genetic investigation of autosomal dominant muscular dystrophy
… family. This segregation was confirmed by a single-strand conformation polymorphism test, then used to test 256 unaffected chromosomes. None possessed MYH7C23628. Two patients from European distal myopathy families phenotypically similar to Laing myopathy, the Voit and Scoppetta families, …
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Genetics of disease resistance: Molecular characterisation of the major histocompatibility Complex Class II genes in Bos species of different origin : A thesis submitted in partial fulfilment of the requirements for the Degree of Master of Science at Lincoln University
… genotyped for variation in exon 2 of BoLA-DRA. A Single Strand Conformation Polymorphism approach was used to genotype the animals and selected cattle were subsequently subjected to direct sequencing of the regions of the genes investigated to reveal nucleotide sequence differences. A total of 10 …
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Mutationen im Leukaemia-Inhibitory-Factor (LIF)-Gen bei wiederholtem Implantationsversagen nach extrakorporaler Befruchtung
… durch Polymerasekettenreaktion (PCR) und die Single-Strand Conformation Polymorphism-Analyse (SSCP). Zeigte sich bei der SSCP-Analyse ein abnormes Laufverhalten in den Elektrophoresebanden, erfolgte anschließend die Sequenzierung des DNA-Abschnittes zur Bestätigung und Identifizierung der …
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Mutational analysis of the DNA mismatch repair genes, hMLH1 and hMSH2, in South African colorectal cancer patients
… in hMLH1 and hMSH2 using exon-by-exon PCR single strand conformation polymorphism (SSCP) analysis. Sixteen pathogenic mutations were found in 14 tumours, 10/22 (45%) from black patients and 4/10 (40%) from caucasian patients. Five tumours presented with two mutations each, one is a compound …
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A molecular investigation of the novel gene underlying autosomal dominant retinitis pigmentosa in a South African family
… events between the adRP locus and a single strand conformation polymorphism (SSCP) in PDEG, and a restriction fragment length polymorphism (RFLP) in TIMP2 provided evidence for the exclusion of these candidate genes. A novel SSCP detected in the promoter region of retinal fascin was …