Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Single-cell detection"”.
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Microfluidic devices for studying early response of cytokine signaling
… of a microfluidic device integrated with cell culture, cell stimulation, and protein analysis as a single device towards an efficient and productive cell-based assay development. In particular, this thesis demonstrates the feasibility of culturing human cancer cells in microliter-volume …
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ESTABLISHING AN IN VITRO MODEL FOR CRISPR-CAS9 SCREENING OF INTERFERON EFFECTORS IN HBV INFECTION
… CHB still leads to cirrhosis and hepatocellular carcinoma, contributing to over one million deaths annually and underscoring the need for improved therapies (World Health Organization 2025). Interferon-alpha (IFN- α), including its pegylated forms, is approved for CHB treatment, but its …
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Detecting and molecular profiling cancer cells in patients
Although tumor cells obtained from human patients by surgical biopsy, image-guided intervention, blood draws or fluid drainage (paracentesis, thoracentesis) are a valuable source for analyzing tumor cells, conventional means of proteomic analysis are limited. Highly sensitive and quantitative …
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Sensitive Detection of Foodborne E. coli O157:H7 by Dendrimer-aptamer Modified Microchannels - with RCA Signal Intensifications
… need for rapid, sensitive and cost-effective detection methods in order to avoid or to respond to outbreaks of such diseases in a timely manner. To this end, a dendrimer-aptamer modified microfluidic detection system with rolling circle amplification (RCA) is developed to detect E. coli …