Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Single-cell Tracking"”.
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The dynamics of anti-tumour responses generated by chimeric antigen receptor-modified immune effector cells
A patient’s own T cells can be genetically modified and amplified in the laboratory to target antigens expressed on tumour cells through the introduction of chimeric antigen receptor (CAR) genes. Despite considerable advances in the treatment of B cell leukaemia using chimeric antigen receptor T …
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Quantitative analysis of 2D and 3D models for epidermal growth factor receptor-dependent cell migration in the context of the extracellular microenvironment
… phenotype and subsequently, how the invasive cell integrates downstream biophysical processes to invade through a three-dimensional (3D) extracellular matrix (ECM). This thesis addresses these questions from a quantitative, engineering perspective, that cell migration in the context of the …
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Beyond Suspension: Light and Growth Dynamics in Immobilised Algal Cultures
… within encapsulating matrices and the loss of cell motility in a biofilm setting. This thesis explores the physiological effect of mechanical confinement on unicellular flagellate Chlamydomonas reinhardtii, a model organism studied extensively in the laboratory. Serving as a study model of …
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A noninvasive screening tool for cell fate determination using raman spectroscopy and machine learning in tissue engineering and microbiology applications
Hematopoietic stem cells (HSCs) are a small heterogeneous pool of self-renewing cells responsible for maintaining the blood and immune system in the human body. The hematopoietic systems of patients suffering from immune or hematological disorders may be reconstituted through the transplantation of …