Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Single nucleus transcriptomics"”.
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An integrated multi-omics approach to improve our understanding of ageing and neurodegeneration
… computational framework to independently analyse single-nucleus transcriptomics and shotgun metagenomics data types along with their integration at the pathway level. From our transcriptomics analysis on 84 healthy individuals across the human life span, we identified that the astrocytes in …
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Selective Neuronal Vulnerability in Neocortices from Patients with C9ORF72-related Neurodegeneration
… not yet been performed. With recent advances in single-cell and spatial transcriptomic approaches, our hypothesis can now be investigated in an unbiased fashion and at unprecedented resolution. The work in this thesis focuses on identifying selectively vulnerable neurons in the post-mortem …