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Showing 1 to 1 of 1 for “"Single cell heteroplasmy"”.
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Mechanisms Controlling the Segregation of Mitochondrial DNA Heteroplasmy
… alongside healthy ones, in a state termed heteroplasmy. In cases where the proportion of mutant to healthy mtDNA molecules reaches a critical threshold, diverse and multisystem pathological phenotypes begin to appear. While an individual’s mtDNA heteroplasmy level is largely dependent on …