Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Single cell approach"”.
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A Single Cell Approach to TCR Signal Strength
… T lymphocytes (CTLs) play a key role in the cell-mediated immune response against virally-infected and tumourigenic cells, killing their targets through the release of cytolytic granules. T cell receptor (TCR) recognition of foreign peptides presented by Class I MHC molecules stimulates naïve …
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Single-cell approaches to assess hematopoietic stem cell response to matrix cues
Hematopoietic stem cells (HSC) are adult stem cells responsible for life-long hematopoiesis, the production of the full complement of blood and immune cells for hematological and immune systems. HSCs reside in the bone marrow within specialized microenvironments known as niches, comprised of …
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The immunopathogenic mechanism of severe cutaneous adverse reactions to first line anti-tuberculosis drugs
… for FLTD-induced SJS/TEN and DRESS, and using single-cell proteomic and transcriptomic analyses, we aimed to immunophenotype different stages of the reactions. Methods We selected three groups of participants from the IMARI in Africa registry: i) HIV+ FLTD SCAR cases, ii) HIV- FLTD SCAR cases …