Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Single Virus"”.
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The characterisation of Ornithogalum mosaic virus
Ornithogalum mosaic virus (OMV) is the most serious pathogen of commercially grown Ornithogalum and Lachenalia species in South Africa. Although omithogalum mosaic disease was first reported as early as 1940, attempts to purify or characterise the virus(es) were not successful. The extremely …
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HIV-1 strain-specific neutralizing antibody responses and the dynamics of viral evolution
… co-evolution of the transmitted/founder (t/f) virus and earlier strain-specific neutralizing antibody (ssnAb) responses. Here we characterized the viral evolution, ssnAb and bnAbs responses in CAP292, an HIV-1 infected woman who developed bnAb responses from one year post infection. We used …
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Israeli acute paralysis virus (IAPV) and deformed wing virus (DWV) infection progression in honey bees
… are often exposed to and infected by multiple viruses, including deformed wing virus (DWV) and Israeli acute paralysis virus (IAPV). These pathogens are major contributors to high numbers of colony failures, threatening the supply of pollination services in agriculture. However, understanding …
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Predicting the Interactions of Viral and Human Proteins
… taken place between the proteins of the virus and human proteins. The current computational models for predicting these interactions consider only single viruses for which extensive prior knowledge is available. The two prediction frameworks in this dissertation, DeNovo and DeNovo-Human, …
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Single molecule fluorescence studies of biomolecular interactions
Single molecule fluorescent techniques have become standard approaches to study protein-DNA interactions. However, these techniques have largely been confined by limitations in assays to studying the interaction between simple DNA substrates and a single protein. During my PhD I developed several …
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Single molecule investigation of antiviral signaling
… to antagonize viral invasion. We utilized single-molecule fluorescence in situ hybridization (smFISH) to study viral and antiviral gene expression in individual cells. We precisely quantified kinetics of mRNA expression of RIG-I with respect to IFN- in cells upon infection with Sendai …
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Double emulsion droplet microfluidics and high-throughput measurements of single viruses
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01
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Bacterial colonization of the nasopharynx in paediatric patients with acute respiratory viral symptoms
… possibly because of co-acquisition of both virus and the bacterium in respiratory droplets, with the viral infection then producing mucosal inflammation and injury conducive to bacterial invasion. During 2004 and 2005, 495 nasopharyngeal aspirate specimens (NPA) for children up to 5 years of …