Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Single Molecule Sensing"”.
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Atomically thin solid-state nanopore field-effect transistors for single-molecule sensing
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-12-01
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Translocation of a Semiflexible Polymer Through a Nanopore
<p>The transport of a biomolecule through a nanopore occurs in many biological functions such as, DNA or RNA transport across nuclear pores and the translocation of proteins across the eukaryotic endoplasmic reticulum. In addition to the biological processes, it has potential applications in …
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Ion transport in multilayer solid-state nanopores for memory and biosensing applications
… investigating nanoscale transport phenomena and single-molecule sensing, owing to their structural robustness, chemical stability, and ability to simultaneously probe ionic and in-plane currents during biomolecule translocation. This dissertation presents a comprehensive computational framework …
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Surface enhanced Raman spectrometry of C₆₀ in an electron tunneling gap
Nanogap devices have applications in single molecule sensing and single molecule transistors. Nanogap devices comprised of a gold nanowire with a nanoscale gap containing C₆₀ were fabricated using electromigration on a silicon substrate. Raman spectra were obtained for various features of this …
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Structure, property and transport mechanism of water and electrolytes in graphene nanopores
… various applications such as water desalination, single molecule sensing, etc. Understanding water and ion transport mechanisms and properties in membranes is essential to characterize and design membranes for various applications mentioned above. In nanopores, transport mechanisms can differ from …
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Electrokinetic phenomena in nanopore transport
… used to sense and measure properties of single molecules such as DNA. This sensing technique relies on the process of translocation, whereby a molecule in aqueous solution moves through the pore under an applied electric field. The presence of the molecule modulates the ionic current …
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INVESTIGATION OF BIOMOLECULAR INTERACTIONS FOR DEVELOPMENT OF SENSORS AND DIAGNOSTICS
… highly specific recognition processes between biomolecules mediate various crucial biological processes. Uncovering the molecular basis of these interactions is of great fundamental and applied importance. This research work focuses on understanding the interactions of several biomolecular …
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Nanopore-Based Readout of Encoded DNA Nanostructures
Nanopore sensing is a powerful technique for the detection and study of single molecules. The underlying resistive pulse principle relies on molecules modulating an ionic current as they pass through a nanoscale constriction between two reservoirs. The technique has recently been extended to the …
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Tip-based nanolithography and application to molybdenum disulfide devices
… mode atomic force microscopy, (iv) demonstrating single-molecule sensing with monolayer MoS2 nanoribbon-nanopore devices. For TBN of polymer nanostructures, this work found nanometer scale capillary-driven flow governs polymer nanostructure deposition from a heated tip. Heated atomic force …
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Enhanced Rainbow Trapping in Width-graded Chirped MIM Nano-gratings for High-sensitivity Multiwavelength Bio-molecular Detection
… nano-gratings vis-à-vis a nanophotonic sensing platform amenable for integration within a Lab-on-a-Chip Point-of-Care system. Theoretically, we delineate the four principal surface plasmon polariton coupling and its interaction mechanisms in subwavelength gratings, thus showing their …