Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Single Channel Recordings"”.
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Understanding The Single Channel Behavior Of Glua3 Receptors
… were compared to whole cell electrophysiological recordings. A correlation between the degree of lobe closure and maximal currents was discovered; that is, the greater the degree of LBD closure, the larger the measured currents. However, as more information relating LBD closure to channel …
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Silicon nanopore patch clamp device for measuring single ion channel activity
… functioning as well as high-throughput ion channel screening for early drug development research. In 1991 Erwin Neher and Bert Sakmann received the Nobel Prize for their invention of the patch clamp, which is based on the formation of a high resistance seal between a glass micropipette and a …
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Voltage-dependent gating at the selectivity filter of the MthK K+ channel.
Voltage-dependent K+ channels can undergo a gating process known as C-type inactivation. This type of gating consists of entry into a nonconducting state that may involve conformational changes near the channel's selectivity filter. However, the details of the underlying mechanisms are not clear. …
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METFORMIN, CLIC1 AND TRANSCRANIAL STIMULATION: THE BASIS OF A NEW TARGETED THERAPY AGAINST GLIOBLASTOMA RELAPSE
… by NMR, MicroScale Thermophoresis, and single-channel patch-clamp experiments. However, due to the blood brain barrier, the high concentration of metformin (10mM) required to inhibit tumor progression, which has been beneficial in other types of tumors, cannot be reached in the brain. As …