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Showing 1 to 1 of 1 for “"Singe-cell genomics"”.

  1. Measuring ongoing chromosomal instability in single-cell DNA sequencing data

    … computational tool to correctly estimate single-cell ploidy and replication status. Cancer cells often exhibit DNA copy number aberrations and can vary widely in their ploidy as a consequence. Correct estimation of the ploidy of single cell genomes is crucial for many aspects of downstream …

    cambridge Repository record for Measuring ongoing chromosomal instability in single-cell DNA sequencing data (opens in a new tab)