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Showing 1 to 2 of 2 for “"Simulation-based benchmark"”.

  1. Probabilistic Model-Based Approach to Evolutionary Analysis of Non-Coding Sequences

    … analyze non-coding sequences, which are based on probabilistic models of sequence evolution. We present a probabilistic framework for finding the locations of insertions and deletions (indels) in a multiple alignment. Its performance is found to be better than that obtained by a …

    uiuc Repository record for Probabilistic Model-Based Approach to Evolutionary Analysis of Non-Coding Sequences (opens in a new tab)

  2. Alternative splicing and single-cell RNA-sequencing: a feasibility assessment

    … scRNA-seq data. To address this, I performed a simulation-based benchmark of isoform quantification software developed for bulk RNA-seq when run on scRNA-seq. I made two important findings. Firstly, I found that isoform quantification software performs poorly when run on Drop-seq data, but …

    cambridge Repository record for Alternative splicing and single-cell RNA-sequencing: a feasibility assessment (opens in a new tab)