Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 105 for “"Silica Nanoparticles"”.
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Development of Super Hydrophobic Surfaces using Silica Nanoparticles
… glass substrate (SiO2) using the functionalized silica (SiO2) nano particles. SU8, Polydimethylsiloxane (PDMS) and Methyphenyl Resin SR355 polymer are being used as binder for Silica nanoparticles to stick on glass substrate. Measurements of contact</p>
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Development of tandem catalytic systems utilizing mesoporous silica nanoparticles
… Using mesoporous materials, mesoporous silica nanoparticles, specifically, as supports and compartmentalization tools in tandem catalysis can increase recyclability and durability, making an even more efficient and green catalytic system. MSN makes an ideal support for tandem catalysis …
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Toxicity and drug delivery ability of bio-inspired silica nanoparticles
Silica nanoparticles are already being used for a number of diagnostic and therapeutic applications. This work focused on the use of bio-inspired silica as a potential drug delivery agent and the toxic effect produced due to their small size. Using two bio-inspired drug encapsulation methods and a …
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Silica nanoparticles as vehicles for therapy delivery in neurological injury
… the inefficient delivery of therapeutic drugs, nanoparticles have become a major field of exploration for medical applications. Based on their material properties, they can help treat disease by delivering drugs to specific tissues, enhancing detection methods, or a mixture of both. …
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Formulation Devlopment Of Mesoporous Silica Nanoparticles As An Injectable Delivery System
… robust injectable carrier based on Mesoporous Silica Nanoparticles (MSN) for drug/drug combination therapies. The objective of my dissertation was to optimize surface functionality, particle shape and methods of colloidal stabilization of mesoporous silica by PEG for delivery of drug/drug …
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Critical considerations in development of mesoporous silica nanoparticles for biological applications.
In the past ten years, mesoporous silica nanoparticles have been some of the hottest materials investigated for biomedical use. Mesoporous silica nanoparticles are size-controllable and discrete particles with high surface area, large pore volume, and easy surface modification properties. These …
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Terpyridine Functionalized Dye-Doped Silica Nanoparticles (DDSN) for Detection of Metal Ions
<p>In an effort to synthesize a novel silica nanoparticle platform for the fluorescent sensing of metal ions and future use in QDA, we synthesized from the bottom up a novel 2, 2’: 2’, 6- terpyridine functionalized fluorescein doped silica nanoparticle system capable of the sensitive detection of …
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PREPARATION AND EVALUATION OF MESOPOROUS SILICA NANOPARTICLES FOR PLATINUM-ACRIDINE ANTICANCER DRUG DELIVERY
Mesoporous silica nanoparticles (MSNs) have a wide range of applications in the basic and biomedical sciences. Because of their unique pore structures and physicochemical properties, MSNs have recently attracted major attention as an inert carrier material in oncology drug formulations. In this …
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The Safety and Immunostimulatory Properties of Amorphous Silica Nanoparticles <10 nm in Diameter
Humans are exposed to high levels of amorphous silica on a daily basis, via the diet and the use of cosmetic and pharmaceutical products. Amorphous silica particles (10-200 nm) have also been developed for use in biomedical applications, including as binding agents in tissue repair, drug and gene …
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Design, Synthesis and Characterization of Porous Silica Nanoparticles and Application in Intracellular Drug Delivery
… intracellular bacteria. Among them, the porous silica nanoparticles deserve special attention due to their multifunctional properties such as high drug loading, controlled drug release and targeting of organs/cells. A review of the functional requirements of an ideal drug delivery system is …
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Dendrimer Modified Silica Nanoparticles as Fluorescent Chemosensors for the Detection of Copper and Cyanide Ions
<p>A series of silica nanoparticle-based fluorescent chemosensors were synthesized for the sensitive and selective detection of Cu<sup>2+ </sup>ions in aqueous solution and subsequent CN<sup>-</sup> ion detection. Silica nanoparticles (SNP) were modified with branching polyamidoamine (PAMAM) …
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Surface Activity at the Air-Water Interface and Self-Stratification of Silica Nanoparticles Functionalized with Tri-Methoxy Poly(ethylene glycol) Silane
<p>Aggregated silica nanoparticles (SNPs) have been functionalized with tri-methoxy poly(ethylene glycol) silane (mPEG silane), end-capped with a methyl group. This functionalization imparts surface activity at the air-water interface due to the hydrophobic nature of the end-capped methyl group. To …
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Surface Modification of Nanoparticles Using Controlled Radical Polymerization For Designed Interfaces
… to graft polymers from the surface of colloidal silica nanoparticles for incorporation in polymers to make composites. </p> <p>In the first part of this work, a new strategy based on Marcomolecular Design via Interchange of Xanthates (MADIX) polymerization was demonstrated to graft polymer …
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Effects of silica nanoparticle surface treatment and average diameter on the physical and mechanical properties of poly(dimethylsiloxane)-silica nanocomposites
… of this thesis was to quantify the effects of silica nanoparticle surface treatments and average silica nanoparticle diameter on various macroscopic properties of poly(dimethylsiloxane)-silica nanocomposites, specifically stiffness, wettability, and permeability to organic solvents. …
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Aspects of bioorganic chemistry - a). Development of caffeine-aptamer for coffee decaffeination; b). Study of 1,8-naphthalimide derivatives as fluorescent probes; c). Encapsulation of DNA by silica nanoparticles
Research described in this thesis encompass three aspects of bioorganic chemistry: Caffeine- binding aptamers were sought to remove caffeine from coffee brew. Toward this goal, theophylline carboxylic acid and caffeine carboxylic acid were synthesized, and immobilized to ω-aminohexyl–agarose. The …
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Incorporation of silica into baroplastic core-shell nanoparticles
… two incorporation strategies for introducing silica nanoparticles were developed. The pre-emulsion strategy incorporated hydrophobized silica nanoparticles inside the core-shell nanoparticles to create core-shell-shell nanoparticles. The post-emulsion strategy incorporated charged silica …
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GROWTH OF SILICA-BASED NANOPARTICLES: CONTROLLING STRUCTURE AND FUNCTION
Silica chemistry provides a uniquely tunable platform for nanoparticle synthesis, where particle size, nanoscale morphology, and surface properties can be precisely controlled. Recent advances demonstrate that conveniently accessible parameters, including silica precursor chemistry, solvent, and …
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Multiplexed nanoparticle-based immunoassays
… and luminescent properties of fluorophores and nanoparticles. Epi-fluorescence microscopy, confocal laser scanning microscopy and programmable array microscopy were used to detect signals from mixtures of conventional organic fluorophores, quantum dots and silica nanoparticles doped with …
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Comprehensive Study of Semicontinuous Emulsion Polymerisation Processes for Producing Nanoparticles
… effort has been expended on research in polymer/silica core-shell hybrid systems due to their promising applications in surface coatings and biotechnology. Comparing with conventional batch process, hybrid particles obtained by semicontinuous surfactant-free emulsion polymerisation can …
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