Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 30 for “"Silencers"”.
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Development of next-generation optical neural silencers
The ability to rapidly and safely silence the electrical activity of individual neurons or neuron populations is invaluable in the study of brain circuit mapping. The expression of light-driven ion channels and pumps allows these pathways to be observed, mapped and controlled with millisecond …
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Prediction of performance criteria for passive heating ventilation and air conditioning silencers
… x 2ft cross sectional area rectangular passive silencers for various internal geometries using either fiberglass or mineral wool linings. The performance criteria predicted by the regression equations is compared with the measured data; also, results are provided which display the effect the …
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Before and after DUX4: deconstructing its web of silencers and defining its long-term impact on cellular processes
… by several previously identified D4Z4 silencers: SETDB1, ATF7IP, SIN3A/3B, and LRIF1. The reporter system also showed promise as a robust platform for further discovery of FSHD therapeutics and disease modifiers, with candidate therapeutic p38 pathway inhibitors showing increased …
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The acoustic modelling of dissipative elements in automotive exhausts
… and experimental testing of both dissipative silencers and catalytic converters is reported here, although dissipative silencers are of primary interest. The models examined are formulated with a view to introducing them into commercial software aimed at the acoustic design of automotive …
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Algorithms for simulating human pre-mRNA splicing decisions
… exonic splicing enhancers, exonic splicing silencers, and intronic splicing enhancers. I used ExonScan to test various aspects of human splicing, including correlation of splicing signal strength with tissue expression levels, the effectiveness of experimentally determined exonic splicing …
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Development of a test facility for making in-duct sound measurements according to Astm E477-1984
Duct silencers must reduce sound levels enough to be noticed by the human ear. By placing the appropriate duct silencer in the air-conditioning duct system, sound levels in rooms where noise is a problem can be significantly reduced. Only through insertion loss measurements can the appropriate …
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Identifying Splicing Regulatory Elements with de Bruijn Graphs
… exonic enhancers and 3080 putative exonic silencers for human genes, with lengths varying from 6 to 15 nucleotides. Many of the predicted SREs overlap with experimentally verified binding sites. My model provides a novel method to predict variable length putative regulatory elements …
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Investigations into the Phage-Host Dynamics of Streptomyces
… silences foreign DNA in bacteria. Xenogeneic silencers have been shown to bind to and silence prophage genes genomes and many phages encode for proteins that inhibit xenogeneic silencers, indicating that xenogeneic silencers may have a role in anti-phage defence. However, deletion of these …
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Acoustic metamaterials : microperforated shell and Helmholtz resonator
… single-layer silencer. In turn, two single-layer silencers are combined to form a double-layer silencer, which in theory double performance on noise blocking of the single-layer silencer. Theoretical models of slit-type Helmholtz resonators and silencers are developed completely and well validated …
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Application of microperforated elements in axial fan noise control and silencer design
… were used in fan noise control and in acoustic silencers, where both of the devices are easily accessible by humans.
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From Communicative Silencer to Responsive Listener: Participation and Public Dialogue in Benin
… in which intellectual elite become communicative silencers of the silenced communities including the illiterate, the poor and the underprivileged. Second, the interpretation pays heed to the communicative alternative emerging from the public dialogue experienced during the National Conference …
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Implementation of Refractory Foam Technology for Silencing Small IC Engines
… of porous material, for designing effective silencers for small IC engines. The solution must be lightweight, compact, conformable, and capable of handling the rigors of flight. Throughout the course of this research, many silencer designs were fabricated to take advantage of refractory foam …
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Harnessing Cancer Omics to Inform Precision Oncology
… that can be enhancers of tumor suppressor and silencers of oncogene in colon cancer via whole genome and targeted UCE sequencing from two cohorts. We characterized the tumor microenvironment of melanoma brain metastasis (MBM) during anti-PD1 therapy using single cell RNA sequencing (scRNA-seq) …
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Acoustic and thermal packaging of small gas turbines for portable power
… for both cold intake and hot exhaust gas silencers to reduce the broadband noise. The source noise simulations combined with the measured silencer noise reduction show noise levels below 50 dBA in all directions. A parametric silencer configuration study was carried out to determine the …
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Acoustic Characterization and Preliminary Noise Control of Pneumatic Percussion Tools
… employing commercial-off-the-shelf pneumatic silencers. The outcome of the tests is illustrated in detail in this thesis.
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Representing Europe or National Priorities? Variation among Nordic Presidencies of the Council of the EU in Amplifying or Silencing National Environmental Policy
… in the extent to which they act as amplifiers or silencers of national environmental priorities during their Presidency terms. The Swedish Presidency gravitated most clearly towards the amplifier approach, the Finnish Presidency reflected a more restrained form of amplification, while the Danish …
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H-NS Counter-silencing as a Primary Regulatory Mechanism of Curli Gene Expression in Salmonella Typhimurium
… UV irradiation. Characterization of counter-silencers in Salmonella can help us understand mechanisms of gene regulation that can be extrapolated to other organisms and provide new insights into the evolution of regulatory networks in bacteria.
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Molekulargenetische Analyse eines evolutionär konservierten Silencer-Elements aus dem murinen H19-Locus in Drosophila melanogaster
… ist der molekulare Wirkungsmechanismus des H19-Silencers nicht bekannt. Der evolutionär konservierte Silencing-Mechanismus hat es ermöglicht, Drosophila melanogaster in dieser Arbeit als Modellsystem einzusetzen, um neue cis- und trans-wirkende Faktoren im Prozess des Gensilencings durch den …
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G-Quadruplexes As Molecular Targets For Transcriptional Control
… G4s, kRAS and Bcl-2, act as transcriptional silencers and activators, respectively. kRAS is highly deregulated in 30% of cancers, and its downregulation can decrease tumor cell proliferation and survival. Decreases in Bcl-2 expression result in pro-apoptotic signaling. However, Bcl-2 G41 …
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Role of Polycomb Group Protein Mel18 in Hematopoietic Stem Cell Maintenance
Polycomb group (PcG) proteins are epigenetic gene silencers that have been implicated in stem cell maintenance and cancer development. Genetic and biochemical studies indicate that Polycomb group proteins exist in at least two protein complexes, Polycomb repressive complex 2 (PRC2) and Polycomb …
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