Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Signatures of mutational processes"”.
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The somatic evolution of the canine transmissible venereal tumour
This dissertation investigates the evolution of the canine transmissible venereal tumour (CTVT), a sexually transmitted cancer which manifests as genital tumours in dogs. This cancer first arose in an individual dog several thousand years ago, and has since survived by transfer of living cancer …
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Measuring ongoing chromosomal instability in single-cell DNA sequencing data
… instability is a characteristic hallmark of cancer. It is providing part of the genomic variation that makes cancer so heterogeneous and difficult to treat. Consequently, better insights into the mechanism and dynamics of chromosomal instability are fundamental to understanding and …