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Showing 1 to 1 of 1 for “"SidK"”.
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Study of the Yeast Vacuolar-type ATPase by Electron Cryomicroscopy
… Disease, secretes a protein effector called SidK that binds and inhibits V-ATPases, preventing acidification of lysosomes and promoting survival of the bacterium inside macrophages. The mechanism of V-ATPase inhibition by SidK is not known. The structure of V-ATPases can be analyzed by single …