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Showing 1 to 12 of 12 for “"Sickle cell anaemia"”.
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Sickle cell anaemia in Cameroon : co-inheritance of α-thalassemia, HBB gene haplotypes, clinical & haematological characterisations
Background: Although sickle cell anaemia (SCA) is genetically characterised by a single point mutation, patients can manifest varying degrees of clinical severity due to various genetic modulators that affect the phenotype of this disease. The co-inheritance of alpha-thalassemia (α-thalassemia) has …
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Common causes of bacteraemia among sickle cell anaemia children with fever: evidence from a cross section survey.
Introduction:Sickle cell anaemia is an important cause of morbidity and mortality among Zambian children, with a carrier frequency ranging from 6% – 27%. Infections are the most common cause of mortality among sickle cell children aged between one to five years, accounting for about 30% of the …
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Exploring the quality of life and care needs of children and families affected by sickle cell anaemia in Angola
Sickle cell anaemia (SCA) is the most common and severe type of sickle cell disease (SCD) – a recessively inherited chronic blood disorder associated with increased childhood morbidity and mortality. Children, including adolescents, are particularly susceptible to physical and clinical …
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Haematological and nutritional status of Sudanese women with sickle cell trait and anaemia: does sickle cell trait compromise birth outcomes?
… status of Sudanese women who have both sickle cell trait and sickle cell anaemia and has considered whether women with sickle cell trait experience worse outcomes of childbirth than those without. Non pregnant group with sickle cell anaemia: In this study, (n=39) sickle cell anaemia and …
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Ο ΧΑΛΚΟΣ ΤΟΥ ΟΡΟΥ ΕΠΙ ΟΜΟΖΥΓΟΥ Β-ΘΑΛΑΣΣΑΙΜΙΑΣ ΚΑΙ ΔΡΕΠΑΝΟΚΥΤΤΑΡΙΚΗΣ ΝΟΣΟΥ ΣΕ ΣΥΣΧΕΤΙΣΜΟ ΠΡΟΣ ΤΟΝ ΣΙΔΗΡΟ ΤΟΥ ΟΡΟΥ ΚΑΙ ΤΗΝ ΗΠΑΤΙΚΗ ΛΕΙΤΟΥΡΓΙΑ
… OF B-THALASSAEMIA, 15 HETEROZYGOTES OF SICKLE-CELL ANAEMIA AND 133 HEALTHY PERSONS. THE CONCLUSIONS ARE AS FOLLOW. 1. LIVER FUNCTION WAS FOUND NORMAL AMONG HEALTHY PERSONS AND ALL GROUPS OF PATIENTS. 2. SERUM NON LEVELS WERE FOUND IN NORMAL LIMITS AMONG HEALTHYPERSONS, HETEROZYGOTES OF …
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The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa
… explanation. I first became interested in the sickle-cell anomaly in 1951, while employed as a medical officer to an asbestos r::iining group in Southern .Rhodesia. Here I had :for investigation a population of several thousand adult male Bantu, very mixed as to tribe, drawn from a wide area of …
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The sickle-cell trait: A study of its distribution and effects in some Bantu tribes of South Central Africa
… explanation. I first became interested in the sickle-cell anomaly in 1951, while employed as a medical officer to an asbestos r::iining group in Southern .Rhodesia. Here I had :for investigation a population of several thousand adult male Bantu, very mixed as to tribe, drawn from a wide area of …
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A cross-sectional study of patients presenting to an urban emergency department in Mwanza, Tanzania
… In the paediatric population (<14 years), sickle cell anaemia in crisis, hydrocephalus and diffuse traumatic brain injury were the top medical, surgical and trauma diagnoses respectively. The most common complaints among the patients presenting to the ED were gastrointestinal complaints …
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Human population history and its interplay with natural selection
… with a protective effect against malaria, sickle-cell anaemia and $\beta^0$ thalassemia (Chapter 6). I found that although this model can reproduce the disjoint ranges of different variants typical of the former, it is incompatible with overlapping distributions characteristic of the …
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Prediction of Physicochemical Properties For Fe3+ Chelating Agents
… exceeds the levels catered for by their natural cellular buffering mechanisms, causing free radical formation via the Fenton reaction and ultimately, therefore, leading to oxidative stress. In such situations, for example in repeatedly transfused patients suffering from (3-thalassaemia or sickle …
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ΤΟ ΕΠΙΠΕΔΟ ΤΟΥ 2,3-ΔΙΦΩΣΦΟΡΟΓΛΥΚΕΡΙΝΙΚΟΥ ΟΞΕΩΣ ΤΩΝ ΕΡΥΘΡΩΝ ΑΙΜΟΣΦΑΙΡΙΩΝ ΣΤΗΝ ΔΡΕΠΑΝΟΚΥΤΤΑΡΙΚΗ ΝΟΣΟ
… IN 32 CONTROL-SUBJECTS; II) IN 18 PATIENTS WITH SICKLE-CELL ANEMIA; III) IN 23 PATIENTS WITHSICKLE-THALASSEMIA; IV) IN 51 INDIVIDUALS WITH SICKLE-CELL TRAIT AND V) IN 18INDIVIDUALS WITH B-THALASSEMIA TRAIT. IN GROUP I, 2,3 DPG LEVEL WAS SIGNIFICANTLY HIGHER IN WOMEN THAN IN MEN AND A NEGATIVE …