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Showing 1 to 1 of 1 for “"Shp2 (Src Homology 2 Domain-containing Protein Tyrosine Phosphatase 2)"”.
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The intramolecular domain interactions and phosphatase activation mechanisms of Shp2
Shp2 (Src Homology 2 Domain-containing Protein Tyrosine Phosphatase 2) is a pivotal player in various signaling pathways in response to growth factors. It contains two SH2 domains (N-SH2 and C-SH2), a phosphatase catalytic domain and a C-terminal tail containing two tyrosyl phosphorylation sites. …