Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Short-term synaptic plasticity"”.
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Pannexin-1 modulates short-term synaptic plasticity by facilitating endocannabinoid transport
… outside of reported involvement in modulating synaptic plasticity in the form of long-term potentiation and long-term depression. The mechanisms by which Panx1 contributes to synaptic physiology are largely unknown. Its high expression in many brain regions (including the hippocampus), …
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The role of short term synamptic plasticity in temporal coding of neuronal networks
Short term synaptic plasticity is a phenomenon which is commonly found in the central nervous system. It could contribute to functions of signal processing namely, temporal integration and coincidence detection by modulating the input synaptic strength. This dissertation has two parts. First we …
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Molecular Mechanisms of Presynaptic Plasticity and Function in the Mammalian Brain
Synaptic plasticity describes efficacy changes in synaptic transmission and ranges in duration from tens to hundreds of milliseconds (short-term), to hours and days (long-term). Short-term plasticity plays crucial roles in synaptic computation, information processing, learning, working and …
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Regulation of Synaptic Vesicle Trafficking at Central Synapses
… inter-neuronal communication in the brain. At presynaptic terminals, synaptic vesicles fuse with plasma membrane in response to electrical stimulation, followed by rapid retrieval to the terminal and re-organization for reuse. Thus, synaptic vesicle trafficking is of interest as to where …
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Dynamics of phase locking in neuronal networks in the presence of synaptic plasticity
… the combined effects of individual cells and synaptic connections whose properties change dynamically. The properties of individual cells and synapses can often be characterized by driving the cell or synapse with inputs that arrive at different phases or frequencies, thus producing a …
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Large-scale neuronal networks: from simulation technology to the study of plasticity-driven cognitive processes
… consensus in the neuroscientific community that synaptic mechanisms, such as short-term synaptic plasticity and structural synaptic plasticity underlie cognitive processes like working memory and learning. Part III of this thesis is devoted to developing simulation and theoretical frameworks that …
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TRPM5 Channels Contribute to Persistent Neural Activity and Working Memory
… is a type of memory that is active only for a short period of time (Fuster and Alexander, 1971; Goldman-Rakic, 1992). A common example of working memory is our ability to hold a phone number in our minds transiently, until it is dialed. Working memory is critical for many cognitive tasks, such …
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Determining how stable network oscillations arise from neuronal and synaptic mechanisms
… the relationships between the cellular and synaptic properties that give rise to stable activity in the form of phase maintenance, across different frequencies in a well-suited model system, the pyloric network of the crab Cancer borealis. The pyloric network has endogenously oscillating …
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The effects of anaesthetic agents on synapses of lymnaea stagnalis (L.)
… inhibition and decreased excitation at the synaptic level within an invertebrate model system, something which cannot readily be done in vertebrate systems. This was achieved by carrying out experiments using both the above mentioned anaesthetics on the whole animal, isolated brain and …