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Showing 1 to 20 of 33 for “"Short chain fatty acids (SCFAs)"”.

  1. Development of a headspace solid-phase microextraction (HS-SPME) procedure for the determination of short-chain fatty acids (SCFAs) in activated sludge by GC-FID

    Cheng, Shiyan

    … is added into the wastewater treatment system. Short-chain fatty acids (SCFAs), an energy source of the bioorganisms, are produced during activated sludge digestion, and play a significant role in phosphorus and nitrogen removal as well as the removal of organic materials during the process of …

    emich Repository record

  2. REGULATION OF T CELLS AND TISSUE INFLAMMATION BY SHORT CHAIN FATTY ACIDS

    Park, Jeong Ho

    … in the host. Intestinal microbiota produce short chain fatty acids (SCFAs) via dietary fiber fermentation. SCFAs have profound effects on the immune system. We investigated the roles of SCFAs in regulating T cell differentiation and tissue inflammation. We found that SCFAs regulate T cell …

    purdue-thes Repository record

  3. THE ROLE OF GUT METABOLITES ON REGULATION OF INTESTINAL IMMUNITY

    Kim, Myunghoo

    … the role of gut metabolites, specifically short chain fatty acids (SCFAs) and retinoic acid (RA), in regulation of intestinal immune responses. Our research revealed novel pathways that SCFAs and RA use to contribute to anti-bacteria immunity through modulation of epithelial cells and …

    purdue-thes Repository record

  4. Bioaccessibility and metabolism of anthocyanins: effects of fermentation, encapsulation, and microbiota interactions

    Borges, Larissa Lorrane RodriguesUniversidade Federal de Viçosa2025

    … and enhanced the production of metabolites and short-chain fatty acids (SCFAs) during the colonic phase. Cyanidin-3-glucoside exhibited superior antioxidant and anti- inflammatory effects compared to its main metabolites, significantly reducing reactive oxygen species and pro-inflammatory …

    brazil-ufv Repository record

  5. Microbial metabolites and graft-versus-host disease in patients undergoing allogeneic hematopoietic cell transplant

    Cagle, Robin2026

    … lower levels of endogenous secondary bile acids in GvHD, particularly lithocholic acid and derivatives (p=0.004/padjusted = 0.02, fold change (FC) = 0.23). There was a 100-fold lower median abundance (p=0.002 and FC < 0.01) and 20-fold lower median diversity of bacterial bile acid …

    washington Repository record

  6. On-trap derivatization of short-chain fatty acids

    Mattieson, Mace2011

    … modulate immune response by the production of short-chain fatty acids (SCFAs). There is a need for rapid, selective analytical methodology capable of trace analysis of SCFAs in complex biological matrices. Previous studies by others using multibed-sorbent traps, solid phase microextraction …

    emich Repository record

  7. The Role of Short-Chain Fatty Acids on Intestinal Epithelial Cell Migration

    Bilotta, Anthony JThe University of Texas Medical Branch at Galveston2022

    … and abroad. Dietary fiber is fermented into short-chain fatty acids (SCFAs) by the gut microbiota and is vital to proper gut function. Previous studies have found that diets lacking fiber, SCFAs, or receptors for SCFAs predispose both animals and humans to IBD and colorectal cancer. However, …

    utmb Repository record

  8. Applications of Proton Transfer Reaction and Selected Ion Flow Tube Mass Spectrometry in Health Monitoring

    Lourenҫo, Célia Maria FarinhaThe Open University2017

    … i.e. significantly increased levels of short-chain fatty acids (SCFAs), ketones, alcohols and aldehydes were found in the faecal headspace of diabetic mice, and a possible link between gut microbiota and type 2 diabetes is demonstrated. The use of VOCs as a screening tool of colorectal …

    the-open-u Repository record

  9. Microbiota regulate short chain fatty acids and influence histone acylations in intestinal epithelial cells.

    Fellows, Rachel ClaireUniversity of Cambridge2020

    … dietary fibres. In this process, they produce short chain fatty acids (SCFAs) such as butyrate, an important energy source for intestinal epithelial cells. SCFAs are chemically related to histone acylations, a growing number of post-translational modifications that include histone acetylation, …

    cambridge Repository record

  10. Small Proline Rich Protein-2 Expression and Regulation in the Caco-2 model of Intestinal Epithelial Differentiation along the Crypt-Villus Axis

    Hui, Patrick J. H.2008

    … by the protein kinase A pathway (PKA) and short chain fatty acids (SCFAs). Differentiation-dependent SPRR2 expression was examined in cytoskeletal-, membrane-, and nuclear-enriched fractions by immunoblotting and confocal immunofluorescence. We studied the effect of SCFAs, known inducers of …

    queens Repository record

  11. Co-Delivery of Peptide QK and WKYMVm for Minimally Invasive Therapeutic Angiogenesis in Treating Critical Limb Ischemia

    Pang, Yuan2024

    … QK and WKYMVm. The polymer bears pendant short-chain fatty acids (SCFAs) that have the potential to polarize M2 macrophages and modulate the immune response. The system is also degradable into non-acidic products through intramolecular cyclization. In this work, we investigated the …

    queens Repository record

  12. Butyrate Sensing by Campylobacter jejuni Impacts Bacterial-Host Interactions

    Goodman, Kyle Nicholas2022

    … beneficial vitamins and metabolites, including short-chain fatty acids (SCFAs) and lactate. Due to the abundance and intestinal distribution of these metabolites, bacterial pathogens can use them as biogeographical cues to discriminate among different regions of the host intestines. Indeed, …

    utswmed Repository record

  13. Applications of LC-MS metabolomic profiling in inflammatory bowel disease and the development of derivatisation methods to enhance selective detection of certain compound classes

    Alothaim, IbrahimUniversity of Strathclyde2018

    … included four sphingosine bases.;The analysis of short chain fatty acids (SCFAs) by LC-MS is a problem since they are too volatile to give good responses. SCFAs are potentially important makers for IBD. A quantitative LC-MS method for acetic, propionic, butyric and lactic acids was developed by …

    strathclyde Repository record

  14. Community Composition and Function of the Hindgut Microbiome in Seaweed-Eating Marine Fish

    Facimoto, CesarResearchSpace@Auckland2024

    … nutrition, fermenting dietary macroalgae to short-chain fatty acids (SCFAs) that benefit the host. Microbial communities assist the fish host overcome nutritional limitations (e.g., protein, energy and vitamins). It is unclear which taxonomic groups contribute to the break down of dietary …

    auckland-ms Repository record

  15. Butyrate-Induced Expression of Proglucagon: Implications for Enteroendocrine Signaling and Intestinal Growth

    Woodard, Jennifer NicoleUniversity of Illinois at Urbana-Champaign2015

    … and obesity. Evidence suggests that fibers and short-chain fatty acids (SCFAs), particularly butyrate, are classes of nutrients capable of regulating the proglucagon gene. To examine this, we treated enteroendocrine L cells with butyrate and found increased proglucagon mRNA abundance. However, …

    uiuc Repository record

  16. Butyrate-induced expression of proglucagon: implications for enteroendocrine signaling and intestinal growth

    Woodard, Jennifer NicoleUniversity of Illinois at Urbana-Champaign2010

    … and obesity. Evidence suggests that fibers and short-chain fatty acids (SCFAs), particularly butyrate, are classes of nutrients capable of regulating the proglucagon gene. To examine this, we treated enteroendocrine L cells with butyrate and found increased proglucagon mRNA abundance. However, …

    uiuc Repository record

  17. LACTICASEIBACILLUS PARACASEI DSM 34154 (L. CASEI DG®) IN PRECLINICAL AND CLINICAL STUDIES AND ITS GENETIC STABILITY OVER A DECADE OF INDUSTRIAL PRODUCTION

    BRUNELLI, LAURAUniversità degli Studi di Milano2024

    … IBS patients, notably by altering short-chain fatty acids (SCFAs) relative proportion, indicating its potential role in alleviating IBS symptoms. This study also highlights the need to identify predictive biomarkers for tailoring personalized probiotic management strategies. …

    milano Repository record

  18. The gut-brain axis in seizure susceptibility: A role for microbial metabolite S-equol

    Bouslog, Allison FayeVirginia Tech2021

    … including neurotransmitters, short chain fatty acids (SCFAs), lactate, vitamins, and S-equol. Furthermore, the gut microbiota is crucial for neurodevelopment, indicating that the gut-brain axis may be involved in pediatric seizure-susceptibility. This dissertation reviews …

    vt Repository record

  19. Short Chain Fatty Acids Signaling through the G Protein-Coupled Receptor GPR41 in the Intestine.

    Shaito, Abdullah2010

    … ferment the polysaccharides to produce short chain fatty acids (SCFAs). SCFAs constitute around 70% of the energy source in ruminants and 10-15% in non-ruminants. Recently, SCFAs have been shown to be ligands fortwo G protein-coupled receptors (GPCRs), Gpr41 and Gpr43. We show that Gpr41 …

    utswmed Repository record

  20. Optimization and Application of Metabolomic Assays for Analyzing Diet-induced and Gut Microbiota-derived Short-chain Fatty Acids in Mice and Humans

    Juenemann, Robert M.2016

    … optimize a metabolomic assay to quantify fecal short chain fatty acids (SCFAs), a byproduct of microbial fermentation in the gut, and to apply this assay to health outcomes of RS4 intervention in an adult population with MetS as well as genetically induced obese mice. <strong>Methods:</strong> …

    sdstate Repository record

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