Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Shigellosis"”.
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Characterization of novel virulence factors of Shigella flexneri and development of Caenorhabditis elegans as an animal model for Shigella infection
… Shigella flexneri is the causative agent of Shigellosis, also known as bacillary dysentery, responsible for 5-15% of the global burden of diarrhoeal disease. Despite over 50 years of Shigellosis research, the search for a commercially viable vaccine is ongoing. A thorough understanding of …
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Characterization of novel virulence factors of Shigella flexneri and development of Caenorhabditis elegans as an animal model for Shigella infection
… Shigella flexneri is the causative agent of Shigellosis, also known as bacillary dysentery, responsible for 5-15% of the global burden of diarrhoeal disease. Despite over 50 years of Shigellosis research, the search for a commercially viable vaccine is ongoing. A thorough understanding of …
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Development and characterization of Shigella multiepitope fusion antigen (MEFA) for a broadly protective subunit vaccine against shigellosis with extended utility against enterotoxigenic Escherichia coli.
Shigella spp. remain a notorious and dominant threat to public health, mainly affecting children and with increasing multidrug resistance. Vaccines represent a significant preventive measure against infectious diseases; however, no approved vaccines are currently available to protect against …
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Genomics Approaches to Improve the Recovery of Bacterial Pathogens in Foods
… recovery from baby carrots linked to historical shigellosis outbreak. The addition of the appropriate antibiotics in food enrichment media reduced the relative proportion of competing bacteria in the enrichment cultures and significantly enhanced the recovery of drug-resistant S. sonnei. This …
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Phenotypic characterisation of wild type and mutant strains of adherent invasive Escherichia coli and Shigella, in vitro, ex vivo and in vivo models
… and susceptible genetic background of Shigellosis and Crohn's disease patients, with both microorganisms showing resistance to antibiotics.;Resistance to antibiotics appears to be a factor in gastrointestinal diseases. Therefore, the present study sought to evaluate the key AIEC and …
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Towards the Synthesis of the Unusual Monosaccharides Found in the Shigella sonnei O-Antigen and Analysis of Shigella flexneri 2a Glycoconjugate Vaccine Samples
Shigellosis (bacillary dysentery) is a severe inflammatory diarrhoeal disease in humans caused by the Gram-negative bacteria belonging to the Shigella species. Despite over 60 years of vaccine research, no licensed vaccine to prevent shigellosis is commercially available. Bioconjugate vaccines …
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Factors influencing the growth of Shigella dysenteriae on laboratory media
Thesis (M.S.)--Michigan State College of Agriculture and Applied Science, 1942
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Genetically programmable pathogen sense and destroy/
… Salmonella spp (typhoid fever), Shigella spp (shigellosis) and a variety of enteropathogenic Escherichia coli strains are among the principle bacterial agents that cause this type of diarrhea. Improvements in hygiene and access to adequate nutrition are good strategies but immunization against …
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Chemical and conformational studies of bacterial cell surface polysaccharide repeating units
… diseases including meningococcal disease and shigellosis. This study is composed of two parts: a computational section, which investigates the capsular polysaccharide (CPS) repeating unit (RU) conformations of meningococcal Y and W CPS vaccines and a second experimental component that involves …
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Health impacts of climate change in the older population
… vulnificus septicemia and 1.3 times higher for shigellosis in the elderly. Older women were more vulnerable to scrub typhus than their male counterparts and the most affected region to scrub typhus was in the order of Jeollabuk-do, Chungcheongnam-do and Ulsan. In terms of vocation, farmers, …