Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 25 for “"Sexual transmission"”.
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Development and Evaluation Of HIV gp120 Responsive Microbicide Formulation for the Prevention of HIV Sexual Transmission
Sexual transmission of HIV remains the primary route (75 to 85%) of HIV infection among all new infection cases. Furthermore, women represent the most vulnerable population and are more susceptible to HIV infections than their male counterpart. Thus, there is an urgent need to develop topical …
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Enhancement Of Ebola Virus Infection By Seminal Amyloid Fibrils
… Africa outbreak, numerous occurrences of Ebola sexual transmission were documented. While sexual transmission has the potential to compromise public health eradication efforts and reignite outbreaks, no molecular details of host factors influencing this phenomenon are known. Amyloid fibrils …
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Knowledge level on treatment-as-prevention among HIV sero-positive adults on antiretroviral therapy in three health facilities of Lusaka district in Zambia.
… of viral load (VL) suppression. Thereby averting sexual transmission of new HIV infections. Hence, the study assessed knowledge on treatment-as-prevention among people living with HIV (PLHIV) on ART, and the factors associated with knowledge on TasP in Lusaka district of Zambia. Methods: A cross …
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Positioning for Acceptance: How Women with HIV Infection Manage Their Relationships
… emotional well being of women. Issues of stigma, sexual transmission and ill health render HIV infection a threat to social relationships. Published literature exists that explores aspects of relationship such as social support, motherhood and condom use but the management of relationships has not …
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The impact of sexually transmitted infections and inflammation in the female genital tract and blood on susceptibility to HIV-1 infection and disease progression
… worldwide, most newHIV-1 infections occur by sexual transmission to women. Recent studies in non-human primates have demonstrated that pro-inflammatory cytokine production in the genital tract is necessary for immune cell recruitment and establishment of simian immunodeficiency virus (SIV) …
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College Students' HPV Knowledge and Intention to be HPV Vaccinated
… of men is of great importance given that sexual transmission is the primary mode of spread to women" (p. 261). In recent years, the development of the HPV vaccine has spurred controversy over whether or not males as well as females should obtain the vaccine against this disease. The …
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Consider the Source : The Effects of Adult Sources of Human Immunodefciency [sic] Virus and Sexually Transmitted Infection Prevention Information on Teen Risk Behaviors for Sexually Transmitted Infection
<p>Sexually transmitted infections (STIs), including the Human Immunodeficiency Virus (HIV), are major health problems for adolescents, who represent over 26% of new cases of STIs diagnosed annually in the United States. Half of all HIV cases in people under age 25 result from sexual transmission …
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Novel strategies for characterizing T Cell responses in SIV-infected rhesus monkeys
… the sites of primary infection in the setting of sexual transmission and they are also important sites of immune depletion. If methods for controlling the replication of the virus early after infection in mucosal sites are available, it may be possible to eliminate the virus prior to systemic …
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HIV and other sexually transmissible infections in a cohort of HIV negative homosexual men in Sydney
… on incidence and risk factors for individual sexually transmissible infections (STIs) and STIs as risk factors for HIV acquisition in a community-based cohort of HIV negative homosexual men in Sydney. Nearly half of men aged under 25 years were seronegative to hepatitis A and B infection. The …
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First detection of otarine herpesvirus-1 in South America: Characterizing the epidemiology in a Peruvian pinniped population
… sensitivity in urogenital swabs, suggests a sexual transmission, which is similar to California sea lions. These data provide insight into dynamics of the potentially oncogenic OtHV-1 in a novel ecosystem, emphasizing the importance of continued disease surveillance in vulnerable Peruvian …
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Strategies for sexually transmitted infection partner notification
… to curb it is a priority. The presence of other sexually transmitted infections (STIs) facilitates the sexual transmission of HIV, and the control of STIs has been shown to be an effective way of reducing HIV incidence. One component of the process of STI control is partner notification: a process …
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Growing up on HAART : the experiences and needs of HIV positive adolescents in care and treatment in the Western Cape province of South Africa
… into adolescence and adulthood. Additionally, sexual transmission of HIV remains a problem, and incidence and prevalence rates among South African youth are high. Experience from the developed world indicates that providing effective care and treatment for youth can be a challenging task. In …
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The barrier functions of the cervical mucus plugs and purified mucins against a panel of HIV-1 strains in the contexts of cell-free and cell-to-cell infections
… order to establish a clinical infection during sexual transmission in the female reproductive tract. The cervical tract of a pregnant woman produces a mucin-rich solid material called the cervical mucus plug, which prevents the entry of bacteria and other foreign substances from the vaginal …
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Effect of HIV infection and pregnancy on parameters of vaginal immunity
… in genital tract fluid that play a role in HIV sexual transmission. We focused on two pathways: The NF-KB inflammation pathway that has been implicated in susceptibility to HIV infection, and two interferon pathways that have been associated with antiviral immune defense. We hypothesized that …
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The role of seminal fluid in cervical squamous carcinoma progression: Impact on cell proliferation, EMT, motility and gene expression
… The key cause for cervical cancer development is sexual transmission and persistent infection with high-risk Human Papillomavirus (HPV). However, it takes several years from infection to cervical cancer development, suggesting that other factors contribute to the disease. Exposure of neoplastic …
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Host and viral determinants of flavivirus emergence and pathogenesis
… Chapter 2, I characterize the pathogenesis and transmission capacity of an under-characterized flavivirus, Spondweni virus (SPONV). I show that SPONV causes fetal harm comparable to Zika virus (ZIKV) in a mouse model of flavivirus pathogenesis during pregnancy and that SPONV can be transmitted …
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A Randomized Controlled Trial for Treatment of High-Grade Cervical Lesions Among HIV-Infected Women in Kenya
… of HIV and subsequently increase the risk of HIV sexual transmission from treated women to HIV-uninfected partners. Cryotherapy and LEEP have both been associated with cervical shedding of HIV, but they have never been directly compared to each other and few studies have rigorously studied …
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Functional Expression of ABC Transporters at Blood-tissue Barriers: Relevance to Antiretroviral Drug Tissue Distribution
… antiretroviral therapy to reduce potential sexual transmission of HIV-1 and prevention of HIV-1 associated neurological complications.
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Early adolescent girls in transition in a peri-urban northern Thai community: perceptions of gender role and sexuality
… girls' perceptions of their gender roles and sexuality which places them at risk for contracting STDs and AIDS through sexual transmission. Ethnographic approaches were used to develop a fuller understanding of the specific social and cultural contexts that structure the meanings of gender and …
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Characterization of Fc receptor family proteins in vaginal and endocervical epithelia
… the World Health Organization (WHO) to prevent sexual transmission of HIV-1. Although HAART treatment as prevention (TasP) of HIV has shown promising preliminary results, poor economic feasibility of the method in resource poor settings has yet to be resolved. Since women carry over 50% of the …
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