Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Severe Acute Respiratory Syndrome (SARS)"”.
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Regulation of IRF-3-Dependent Innate Immune Signaling Pathway by the PLpro Domain of Non-Structural Protein 3 (NSP3) of Severe Acute Respiratory Syndrome (SARS) Coronavirus
… of IFN, ensuring their survival and replication. Severe acute respiratory syndrome coronavirus (SARS-CoV) is a highly pathogenic virus that causes severe lung disease in humans and is associated with high mortality rates. SARS-CoV, like all other successful viruses, encode proteins that counteract …
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Thailand's openness and implications for economic and trade policy: an econometric study
… recent internal and external factors such as the severe acute respiratory syndrome (SARS) and avian flu outbreaks, the Indian Ocean tsunami devastation, the Asian financial crisis and domestic economic policy reforms and political instability as well as military coups have affected the efficiency …
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Coronavirus Replication Inhibition by Herbal Extracts
… cause gastroenteritis, hepatitis, and a syndrome similar to multiple sclerosis of humans. The resent severe acute respiratory syndrome (SARS) outbreak has stirred out global, which turned out to be a novel zoonotic coronavirus. SARS is an infectious disease with a high potential for …
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Examining the Association between Brain MRI Measures at 7 Tesla and cognition following COVID-19 Infection
… cognitive, and neurobiological effects of the severe acute respiratory syndrome (SARS-CoV-2) in survivors with milder symptoms are still poorly understood. In this thesis we evaluated cognitive and psychological changes approximately five weeks after a wide range of symptoms in COVID-19 illness …
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Media social responsibility and risk communication : a critical analysis of newspaper headlines of the SARS outbreak
… responsibility in reporting the outbreak of Severe Acute Respiratory Syndrome (SARS). The situation posed the common media paradox where inherent news values encourage dramatic reports and escalation of conflict that, in tum, are criticized as irresponsible. The particular circumstances …
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Use of Structure-And Ligand-Based Drug Design Tools for the Discovery of Small Molecule Inhibitors of Cysteine Proteases for the Treatment of Malaria and Sars Infection
… cysteine protease of P. Falciparum Malaria and Severe Acute Respiratory Syndrome (SARS). A number of potent inhibitors were developed against cysteine protease and hemoglobinase of P. falciparum , referred as Falcipains (FPs), by the structure-based virtual screening of the focused libraries …
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Host Entry Factors for Human Coronaviruses
… its entry requirements. As we learned from the Severe Acute Respiratory Syndrome (SARS) pandemic, this shift in species can have detrimental consequences. Thus, it is imperative that we understand the virus-host interaction during the entry process.</p><p>This dissertation focuses on host entry …
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Neutralising antibody responses in acute hepatitis C and SARS-CoV-2 infection
… preventative and therapeutic interventions. The acute phase of hepatitis C virus (HCV) infection is characterised by two bottlenecks of viral diversity, one at the initiation of infection (selection of transmitted/founder (T/F) variants), and another within 100 days of infection (emergence of fit …
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Cofactors in Coronavirus Entry
… is facilitated by proteolytic cleavages. The severe acute respiratory syndrome (SARS) coronavirus S proteins rely on host cell proteases for fusion activation. I identified the human lung transmembrane serine protease, TMPRSS2, as an important factor for SARS coronavirus entry. TMPRSS2 …
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Participatory epidemiology : harnessing the HealthMap platform for community-based disease outbreak monitoring
… factors, emerging infectious diseases such as Severe Acute Respiratory Syndrome (SARS), drug-resistant tuberculosis, and 2009 HiNi continue to have significant impact on morbidity, mortality, and commerce worldwide. Early warning and detection of outbreaks plays an important role in protecting …
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The Landscape of Host Transcriptional Response Programs Commonly Perturbed by Infectious Pathogens: Towards Host-Oriented Broad-Spectrum Drug
… and spread of diseases such as HIV/AIDS, Severe Acute Respiratory Syndrome (SARS), avian influenza, and the threats of bioterrorism have made infectious diseases major public health concerns. Despite many successes in the discovery of anti-infective medications, the treatment of infectious …
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Genetics and functions of the SARS coronavirus spike protein
The SARS-Coronavirus (SARS-CoV) is the etiological agent of the severe acute respiratory syndrome (SARS). The SARS-CoV spike (S) glycoprotein mediates membrane fusion events during virus entry and virus-induced cell-to-cell fusion. Investigations, described herein, have focused on the genetic …
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The analysis, design, and development of a digital contact tracing prototype application for the identification of passengers in the event of a biological threat scenario onboard an airplane
… to global health. In 2003, the emergence of severe acute respiratory syndrome (SARS) showed the potential of a contagion to emerge, spread and affect the health, social and economic life of people globally. Most recently, we have experienced the global spread of the 2019 novel coronavirus …
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In vitro inhibition of coronavirus replications
… infections was motivated by an outbreak of severe acute respiratory syndrome (SARS). In order to find drugs that treat coronavirus infections, including SARS, we screened traditional medicinal herbal extracts and evaluated their antiviral activities on coronavirus replication. We employed a …
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Animal models for investigating coronavirus heterotypic immunity
… CoVs have occurred in the last 25 years to cause severe pneumonia, most recently the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS)-CoV-2. Coronaviruses therefore continue to pose significant public health burdens, and although significant advances …
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Quantification of replication present in HIV reports and effect of patient movement between wards on MRSA infection
… such as Human Immunodefficiency Virus (HIV), Severe Acute Respiratory Syndrome (SARS) and Swineflu (H1N1) and hospital acquired infections, such as Meticillin-resistant Staphylococcus Aureus (MRSA) and Clostridium Diffcile, are serious health problems which have been tackled by the World …