Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Seven Transmembrane Receptors"”.
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Acidosis Activated GPR68 Promotes Vascular Smooth Muscle Cell Growth
… impact remains unclear. G protein coupled receptors (GPCRs) are seven transmembrane receptors that have wide-ranging functions in cardiovascular physiology and pathophysiology. A sub-family of proton sensing GPCRs has been identified that senses changes in extracellular pH and are activated …
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Ligand Bias by the Endogenous Agonists of CCR7
<p>Chemokine receptors are members of the seven transmembrane receptor (7TMR) superfamily and are regulated by the G-protein coupled Receptor Kinase (GRK)/ b-arrestin system. CCL19 and CCL21 are endogenous agonists for the chemokine receptor CCR7. They are known to be equipotent in promoting Gi/o …
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Pharmacological Studies of the Signal Transduction Pathways of the a 1a-Adrenbrgic Receptor Subtype
Alpha 1-adrenergic receptors (a1-ARs) are a heterogeneous group of G protein- coupled seven transmembrane receptors that mediate the actions of the endogenous catecholamines, norepinephrine and epinephrine. Three 1a-AR subtypes (a1a, a1b, a1d) have been cloned and classified. cpa-ARs couple to …