Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Settore MEDS-08/A - Endocrinologia"”.
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PTH RESISTANCE SYNDROMES: AGE-DEPENDENT CLINICAL PICTURE AND EMERGING UNCOMMON FEATURES
BACKGROUND: The term “PTH resistance syndromes” refers to a group of diseases so far named pseudohypoparathyroidism (PHP). The improvement of knowledge on pathophysiology and genetic background led to the proposal of a new classification that encompasses all the diseases caused by mutations within …
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IMPACT OF MILD AUTONOMOUS CORTISOL SECRETION ONVERTEBRAL FRACTURE RISK
Mild autonomous cortisol secretion (MACS) represents the most frequent hormonal alteration in patients with adrenal incidentalomas (20-50% prevalence) and has been increasingly associated with cardiometabolic and skeletal complications, including fragility fractures, even in the absence of overt …
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A RANDOMIZED STUDY OF THE GLUNOVO REAL-TIME CGM EFFECTIVENESS ON METABOLIC CONTROL IN PATIENTS WITH T2D
Objective: This study aimed to evaluate the effectiveness of the real-time continuous glucose monitoring (RT-CGM) system, Glunovo, in improving glycemic control and patient outcomes in individuals with poorly controlled type 2 diabetes (T2D) compared to traditional self-monitoring of blood glucose …
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THERAPEUTIC POTENTIAL OF TARGETING THE FLNA-REGULATED WEE1 KINASE PATHWAY IN ADRENOCORTICAL CARCINOMAS.
Adrenocortical carcinomas (ACC) are highly aggressive tumors with very limited treatment options. Alterations in cell cycle-related genes have been identified as key ACC drivers, and they are largely present in the most aggressive tumor subtypes. Compared to benign adenomas (ACA), the cytoskeletal …
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COPEPTIN AS A SURROGATE MARKER OF ARGININE VASOPRESSIN:CLINICAL DIAGNOSTIC AND PROGNOSTIC APPLICATIONS IN ENDOCRINE AND NON-ENDOCRINE DISEASES
BACKGROUND AND AIMS. Copeptin is the C-terminal peptide of pre-pro-arginine vasopressin and it is synthetized and released in equimolar amounts as arginine vasopressin (AVP) from the posterior pituitary gland. Due to greater feasibility of laboratory assessment, it is used as a surrogate marker of …
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IGF2R: A NEW PLAYER IN THE INSULIN LIKE GROWTHFACTOR 2 (IGF2) PATHWAY SUSTAINING ADRENOCORTICAL TUMOURS CELL GROWTH
Adrenocortical tumours (ACT) are a highly heterogeneous class of endocrine cancers, ranging from the common adrenocortical adenoma (ACA) to the rare and aggressive adrenocortical carcinoma (ACC). ACT management is currently relying on the surgical approach; however, the identification of novel …