Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Settore MEDS-05/A - Medicina interna"”.
-
ATHEROSCLEROSIS AND ENDOTHELIAL DYSFUNCTION IN THALASSEMIA
In the last decades, thalassemia patients’ survival has dramatically improved thus, new disease-related and age-related comorbidities are emerging. Little is known about the impact of atherosclerotic cardiovascular disease on these patients. The 2021 European Society of Cardiology (ESC) guidelines …
-
CLINICAL AND LABORATORY CHARACTERISATION OF ACQUIRED VON WILLEBRAND SYNDROME
Background: Acquired von Willebrand syndrome (AVWS) is a rare bleeding disorder due to reduced or dysfunctional VWF in individuals without a personal or familial bleeding history. It is associated with systemic diseases such as lymphoproliferative (LPDs) and myeloproliferative neoplasms (MPNs), …
-
ASSOCIATION BETWEEN ATRIAL SIZE AND CEREBROVASCULAR EVENTS: A RETROSPECTIVE, COHORT STUDY
Background: Left atrial enlargement (LAE) is a cardiac structural abnormality linked to cardiovascular risk, including stroke. However, its independent prognostic role in patients without atrial fibrillation (AF) remains unclear. We carried out a prospective cohort study to assess the association …
-
CARDIAC AUTONOMIC CONTROL DURING SLEEP IN PATIENTS WITH MULTIPLE SYSTEM ATROPHY: A PILOT STUDY ON THE IMPACT OF CPAP THERAPY
Objectives To characterize sleep-stage autonomic regulation in multiple system atrophy (MSA) using cardiorespiratory coupling (K2) and symbolic dynamics (0V%, 2UV%, 2LV%) derived from ECG tracings in video‐polysomnography (v‐PSG). The study aims to compare patients with and without sleep‐disordered …
-
SARCOPENIA, LIVER AND CARDIOVASCULAR ALTERATIONS IN A MULTICENTRIC COHORT OF PATIENTS WITH MASLD: EVALUATION OF CLINICAL PRESENTATION AND GENETIC PREDISPOSITION
Background and Aims: Sarcopenia, characterized by the progressive loss of skeletal muscle mass (SMM), strength, and function, is not solely an age-related condition but is also associated with several diseases, including chronic liver disease (CLD) and cardiovascular (CV) disease. …
-
THROMBUS GENERATION UNDER FLOW CONDITIONS IN PATIENTS WITH CIRRHOSIS AND THROMBOCYTOPENIA: THE CIRTAS-STUDY
… The statistical significance was for p<0.05. Results: Eighty-one cirrhotic patients with platelet count <90,000/mm3 were enrolled and grouped in Child-Pugh class A (n=20), B/C (n=41), and B/C with bacterial infection (n=20). Clinical and laboratory characteristics were consistent with …
-
ELUCIDATING THE ROLE OF HET0016 IN AMELIORATING 20-HETE INDUCED OXIDATIVE STRESS AND LIVER INJURY IN B-THALASSEMIA: A NOVEL THERAPEUTIC TARGET
Background: Reactive oxygen species (ROS) are one of the main contributors to pathological outcomes in β-thalassemia, with their generation being a consequence of iron overload and abnormal red blood cell metabolism. We have previously shown that CYP450 mediates ROS production in the liver of a …
-
IMPACT OF INDOOR AIR POLLUTION ON INFLAMMATORY BIOMARKERS AND CARDIAC AUTONOMIC CONTROL IN HEALTHY SUBJECTS AND PATIENTS WITH CONGESTIVE HEART FAILURE (APICE STUDY)
… (Δ%=+1.2% and Δ%=+2.4%, for 1μg/m3 NO2; p=0.005 and p=0.022, respectively), alongside upregulated expression of pro-inflammatory (IL-6 Δ%=8.94% for 10% increase in NO2, p=0.026; TREM-1 Δ%=6.60% for 10% increase in NO2, p=0.025) and anti-inflammatory (IL-10 Δ%=4.18 for 10% increase in NO2, …